Before the rise of specialized libraries such as the Franklin Institute in the second third of the 19th century, this was probably the largest collection in America of books in those subjects.
As American contributions to the literature of science and technology began to proliferate in the 19th century, the Library Company attempted to acquire them all, but by mid-century it began to fall behind.
It is especially useful for studying the popular or public discourses of science and technology, because it is not an isolated history of science collection, but rather is part of a collection of general literature that includes all subjects and genres of print.