Absorption is a route by which substances can enter the body through the skin. Along with inhalation, ingestion and injection, dermal absorption is a route of exposure for toxic substances and route of administration for medication. Absorption of substances through the skin depends on a number of factors, the most important of which are concentration, duration of contact, solubility, physical condition of the skin and part of the body exposed. Certain substances called carriers can be used to greatly increase the amount of other substances that is able to penetrate the skin. Dimethyl sulfoxide (DMSO) is a carrier that is frequently used to transport medication through the skin. This allows treatment to be localized, unlike with ingestion. In zootomy and dermatology, skin is the largest organ of the integumentary system made up of multiple layers of epithelial tissues that guard underlying muscles and organs. ... In general terms, eating (formally, ingestion) is the process of consuming something edible, i. ... Injection has multiple meanings: In mathematics, the term injection refers to an injective function. ... The dermis is a layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... It has been suggested that Blockbuster drug be merged into this article or section. ... In chemistry, concentration is the measure of how much of a given substance there is mixed with another substance. ... Solubility refers to the ability for a given substance, the solute, to dissolve in a solvent. ... Dimethyl sulfoxide (DMSO) is the chemical compound (CH3)2SO. This colorless liquid is an important dipolar aprotic solvent. ...