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Encyclopedia > Acetanilide
Acetanilide
IUPAC name N-phenylacetamide
Identifiers
CAS number 103-84-4
SMILES O=C(C)Nc1ccccc1
Properties
Molecular formula C8H9NO
Molar mass 135.17 g/mol
Density 1.219 g/cm³
Melting point

113–115 °C (235–239 °F) Image File history File links Question_book-3. ... Image File history File links Download high resolution version (1769x1011, 1751 KB) Summary Description: Chemical structure of acetanilide. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... For other uses, see Density (disambiguation). ... The melting point of a crystalline solid is the temperature range at which it changes state from solid to liquid. ...

Boiling point

304 °C Italic text This article is about the boiling point of liquids. ...

Solubility in other solvents 1g/185mL
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

| Water solubility | 0.1g/100mL at 22 °C |- Solubility is a chemical property referring to the ability for a given substance, the solute, to dissolve in a solvent. ... The plimsoll symbol as used in shipping In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals exactly). ... Water is a bent, polar compound and possesses the ability to Hydrogen bond. ...


Acetanilide is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name antifebrin. For other uses, see Solid (disambiguation). ... A trade name, also known as a trading name or a business name, is the legal name of a business, or the name which a business trades under for commercial purposes. ...

Contents

Formation

Acetanilide can be produced by reacting acetic anhydride with either aniline or phenylammonium chloride Acetic anhydride, also known as ethanoic anhydride, is one of the simplest of acid anhydrides. ... Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. ... Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. ...


Properties

This compound is soluble gah hot water. It has the ability to self-ignite if it reaches a temperature of 545 °C, but is otherwise stable under most conditions. Pure crystals are plate shaped, white in colour, and have a sugary aftertaste. Celsius is, or relates to, the Celsius temperature scale (previously known as the centigrade scale). ...


Applications

Acetanilide is used as an inhibitor in hydrogen peroxide and is used to stabilize cellulose ester varnishes. It has also found uses in the intermediation in rubber accelerator synthesis, dyes and dye intermediate synthesis, and camphor synthesis. Acetanilide was used as a precursor in penicillin synthesis and other pharmaceuticals and its intermediates. A reaction inhibitor is a substance that prevents or decreases the rate of a chemical reaction. ... R-phrases , , , , S-phrases , , , ,, , , , Flash point Non-flammable Related Compounds Related compounds Water Ozone Hydrazine Except where noted otherwise, data are given for materials in their standard state (at 25 Â°C, 100 kPa) Infobox disclaimer and references Hydrogen peroxide (H2O2) is a very pale blue liquid which appears colourless in... Cellulose as polymer of β-D-glucose Cellulose in 3D Cellulose (C6H10O5)n is a polysaccharide of beta-glucose. ... For other uses, see Ester (disambiguation). ... Varnish is a transparent, hard, protective finish or film primarily used in wood finishing but also for other materials. ... This does not cite any references or sources. ... Look up dye in Wiktionary, the free dictionary. ... R-phrases 11-20/21/22-36/37/38 S-phrases 16-26-36 RTECS number EX1260000 (R) EX1250000 (S) Supplementary data page Structure and properties n, εr, etc. ... For the Japanese rock band, see Penicillin (band). ... Pharmacology (in Greek: pharmacon is drug, and logos is science) is the study of how chemical substances interfere with living systems. ...


Acetanilide has analgesic and fever-reducing properties; it is in the same class of drugs as acetaminophen (paracetamol). Under the name acetanilid it formerly figured in the formula of a number of patent medicines and over the counter drugs. In 1948, Julius Axelrod and Bernard Brodie discovered that acetanilide is much more toxic in these applications than other drugs, causing methemoglobinemia and ultimately doing damage to the liver and kidneys. As such, acetanilide has largely been replaced by less toxic drugs, in particular acetaminophen, which is a metabolite of acetanilide and whose use Axelrod and Brodie suggested in the same study. An analgesic (colloquially known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). ... An analogue medical thermometer showing the temperature of 38. ... Paracetamol (INN) (IPA: ) or acetaminophen (USAN), is the active metabolite of phenacetin, a so-called coal tar analgesic. ... E.W. Kembles Deaths Laboratory in Colliers Magazine in 1906 Patent medicine is the somewhat misleading term given to various medical compounds sold under a variety of names and labels, though they were, for the most part, actually medicines with trademarks, not patented medicines. ... Year 1948 (MCMXLVIII) was a leap year starting on Thursday (link will display the 1948 calendar) of the Gregorian calendar. ... Julius Axelrod won a Nobel Prize in 1970 Julius Axelrod (May 30, 1912 – December 29, 2004) was an influential American biochemist. ... Methemoglobinemia, also known as met-Hb, is a disorder characterized by the presence of a higher than normal level of methemoglobin in the blood. ... For the bird, see Liver bird. ... The kidneys are organs that filter wastes (such as urea) from the blood and excrete them, along with water, as urine. ... A metabolite is the product of metabolism. ...


In the 19th century it was one of a large number of compounds used as experimental photographic developers. Alternative meaning: Nineteenth Century (periodical) (18th century — 19th century — 20th century — more centuries) As a means of recording the passage of time, the 19th century was that century which lasted from 1801-1900 in the sense of the Gregorian calendar. ... In film developing, photographic developer (or just developer) is a chemical that makes the latent image on the film or print visible. ...


External links

  • Acetanilide MSDS

  Results from FactBites:
 
ACETANILIDE (N-PHENYLACETAMIDE) (727 words)
Acetanilide is an odourless, white flake solid or crystalline powder (pure form); soluble in hot water alcohol, ether, chloroform, acetone, glycerol, and benzene;; melting point 114 C and boiling point 304 C; can undergo self-ignite at 545 C, but is otherwise stable under most conditions.
Acetanilide is used as an inhibitor of peroxides and stabilizer for cellulose ester varnishes.
But acetanilide is not used directly for this application due to causing methemoglobinemia (the presence of excessive methemoglobin which does not function reversibly as an oxygen carrier in the blood).
Acetanilide - Wikipedia, the free encyclopedia (269 words)
Acetanilide is used as an inhibitor in hydrogen peroxide and is used to stabilize cellulose ester varnishes.
Acetanilide was used as a precursor in penicillin synthesis and other pharmaceuticals and its intermediates.
Acetanilide has analgesic and fever-reducing properties; it is in the same class of drugs as acetaminophen (paracetamol).
  More results at FactBites »


 

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