The carbon of the carbonyl has an lone electron available, with which it forms a chemical bond to the remainder of the molecule.
The acetyl radical is a component of many organic compounds, including acetyl-CoA, the neurotransmitter acetylcholine, and the analgesics acetaminophen and acetylsalicylic acid (better known as aspirin).
The introduction of an acetyl group into a molecule is called acetylation.
AcetylCoA acts both as a metabolic "receiving and shipping department" for all classes of biomolecules and as a major source of useful metabolic energy.
The interactions of amino acids with acetylCoA and the citric acid cycle will be studied in protein metabolism.
Under these conditions, acetylCoA is diverted from the citric acid cycle to the formation of acetoacetic and 3-hydroxybutanoic acids.