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Encyclopedia > Adalat

Nifedipine chemical structure
Nifedipine

1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)
-3,5-pyridinedicarboxylic acid, dimethyl ester
CAS number
21829-25-4
ATC code
C08CA05
Chemical formula C17H18N2O6
Molecular weight 346.337
Bioavailability  ?
Metabolism  ?
Elimination half-life  ?
Excretion  ?
Pregnancy category  ?
Legal status  ?
Routes of administration  ?

Nifedipine (brand name Adalat and Procardia) is a dihydropyridine calcium channel blocker. Its main uses are in angina pectoris (especially Prinzmetal angina) and hypertension, although a large number of other uses have recently been found for this agent, such as Raynaud's phenomenon, premature labor, and painful spasms of the esophagus in cancer patients. CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is a term used to describe a pharmacokinetic property of drugs, namely, the fraction of a dose which reaches the systemic circulation. ... The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ... --212. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ... The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... Calcium channel blockers are a class of drugs with effects on the muscle of the heart and the muscles of the rest of the body. ... Hypertension or high blood pressure is a medical condition where the blood pressure in the arteries is chronically elevated. ... In medicine, Raynauds phenomenon is discoloration of the fingers or toes due to emotion or cold in a characteristic pattern in time: white, blue and red. ... Premature birth is defined medically as a birth occurring earlier than 37 weeks. ... The esophagus, oe/œsophagus*, or gullet is the muscular tube in vertebrates through which ingested food passes from the mouth area to the stomach. ... When normal cells are damaged or old they undergo apoptosis; cancer cells, however, avoid apoptosis. ...


See Also

  • Nifedipine - rxlist.com
  • Nifedipine - medlineplus.org


Calcium channel blockers edit
Class I edit

{Verapamil} Calcium channel blockers are a class of drugs with effects on the muscle of the heart and the muscles of the rest of the body. ... Verapamil is a medical drug that acts as a calcium channel blocker. ...

Class II edit

{Amlodipine} {Felodipine} {Nicardipine} {Nifedipine} {Nisoldipine} {Nimodipine} Categories: Stub | Calcium channel blockers ... Felodipine is a calcium channel blocker (calcium antagonist), a drug used to control hypertension (high blood pressure). ... Nimodipine (marketed by Bayer as Nimotop®) is a dihydropyridine calcium channel blocker originally developed for the treatment of high blood pressure. ...

Class III edit

{Diltiazem} Categories: Medicine stubs | Calcium channel blockers ...


  Results from FactBites:
 
Adalat Online, Description, Chemistry, Ingredients - Nifedipine - RxList Monographs (175 words)
ADALAT CC is an extended release tablet dosage form of the calcium channel blocker nifedipine.
ADALAT CC tablets consist of an external coat and an internal core.
ADALAT CC tablets contain either 30, 60, or 90 mg of nifedipine for once-a-day oral administration.
  More results at FactBites »


 
 

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