Still's disease is a form of juvenile rheumatoid arthritis (JRA), characterized by high spiking fevers and transient rashes, named after the English physician Sir George F. Still (1861-1941). The disease was first discovered in children, but now it is also known to occur, less commonly, in adults in whom it is referred to as adult-onset Still's disease. The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // M00-M99 - Diseases of the musculoskeletal system and connective tissue (M00-M25) Arthropathies (M00-M03) Infectious arthropathies (M00) Pyogenic arthritis (M01) Direct infections of joint in infectious and parasitic diseases classified elsewhere (M02) Reactive arthropathies (M023) Reiters disease (M03) Postinfective and reactive arthropathies in diseases classified elsewhere (M05-M14... // M00-M99 - Diseases of the musculoskeletal system and connective tissue (M00-M25) Arthropathies (M00-M03) Infectious arthropathies (M00) Pyogenic arthritis (M01) Direct infections of joint in infectious and parasitic diseases classified elsewhere (M02) Reactive arthropathies (M023) Reiters disease (M03) Postinfective and reactive arthropathies in diseases classified elsewhere (M05-M14... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The Diseases Database is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... MedlinePlus (medlineplus. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Arthritis (from Greek arthro-, joint + -itis, inflammation) is a group of conditions that affect the health of the bone joints in the body. ... See Fever for the Kylie Minogue album; Fever is also a song by Otis Blackwell. ... Red and Anarchist Skinheads is often referred to as RASH. A typical rash A rash is a change in the skin which affects its appearance or texture. ... Motto: Dieu et mon droit (Royal motto; French for God and my right) 3 Anthem: God Save the Queen4 Capital London Largest city London Official language(s) English de facto 5 Government Queen Prime Minister Constitutional monarchy Elizabeth II Tony Blair Establishment 18016 Area  - Total  - Water (%)   244,820 km² (80th... Physician examining a child A physician is a person who practices medicine. ... 1861 is a common year starting on Tuesday. ... For the movie, see 1941 (film) 1941 (MCMXLI) was a common year starting on Wednesday (the link is to a full 1941 calendar). ... A female child A child (plural: children) is a young human, or someone who has not yet reached puberty (someone who is prepubescent). ...

There are several theories about the cause of Still's disease. It has been suggested it may be caused by a microbacterial infection or that it is an autoimmune disorder. However, the cause of Still's disease remains unknown. A microorganism or microbe is an organism that is so small that it is microscopic (invisible to the naked eye). ... Infected (Podcast) is also the name of an internet radio podcast hosted by Martin Sargent. ... Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. ...

Symptoms

Patients with Still's disease usually have body wide symptoms. Usual symptoms include: The term symptom (from the Greek syn = con/plus and pipto = fall, together meaning co-exist) has two similar meanings in the context of physical and mental health: A symptom may loosely be said to be a physical condition which shows that one has a particular illness or disorder (see...

• waves of high fevers that rise to 40 °C (104 °F) which may be accompanied by extreme fatigue
• A faint transient non-itching salmon-colored skin rash can also be observed.
• Flu like pain throughout the body,
• muscle pain

Other symptoms include:: Fever is also the name of an album by Kylie Minogue. ... A degree Celsius (°C) is a unit of temperature named after the Swedish astronomer Anders Celsius (1701-1744), who first proposed a similar system in 1742. ... Fahrenheit is a temperature scale named after the German physicist Gabriel Fahrenheit (1686–1736), who proposed it in 1724. ... Two fatigued men in Tehran The word ‘fatigue’ is used in everyday living to describe a range of afflictions, varying from a general state of lethargy to a specific work induced burning sensation within muscle. ... For the manga by Tsukasa Hôjô, see Rash. ... Pain is an unpleasant sensation which may be associated with actual or potential tissue damage and which may have physical and emotional components. ... Myalgia means muscle pain and is a symptom of many diseases and disorders. ...

• swelling of the lymph glands (lymphadenopathy)
• enlargement of the spleen (splenomegaly) and liver (hepatomegaly)
• sore throat
• pleurisy and pericarditis -- inflammation of the pleura (the lining around the lungs) or the pericardium (the lining around the heart) with fluid accumulation.
• Although the arthritis may initially be overlooked because of the other symptoms, everyone with Still's disease eventually develops pain and swelling in several joints. Though any joint can be affected, some joints (like the wrists) are more likely to be affected by the disease than others.

In mammals including humans, the lymphatic vessels (or lymphatics) are a network of thin tubes that branch, like blood vessels, into tissues throughout the body. ... Lymphadenopathy is swelling of one or more lymph nodes. ... The spleen is a ductless, vertebrate gland that is not necessary for life but is closely associated with the circulatory system, where it functions in the destruction of old red blood cells and removal of other debris from the bloodstream, and also in holding a reservoir of blood. ... Splenomegaly is an enlargement of the spleen. ... The liver is one of the largest internal organs of the human body. ... Hepatomegaly is an enlargement of the liver (swelling). ... Also see Pharyngitis Sore Throat is a legendary British noisecore band, credited among others with inventing the genre. ... Pleurisy, also known as pleuritis, is an inflammation of the pleura, the lining of the pleural cavity surrounding the lungs, which can cause painful respiration and other symptoms. ... Pericarditis is inflammation of the pericardium. ... Inflammation is the first response of the immune system to infection or irritation and may be referred to as the innate cascade. ... In anatomy, the pleural cavity is the potential space between the lungs and the chest wall. ... The lungs flank the heart and great vessels in the chest cavity. ... The pericardium is a double-walled sac that contains the heart and the roots of the great vessels. ... The heart and lungs (from an older edition of Grays Anatomy) The heart (Latin cor) is a hollow, muscular organ in vertebrates that pumps blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in annelids, mollusks, and arthropods. ... Arthritis (from Greek arthro-, joint + -itis, inflammation) is a group of conditions that affect the health of the bone joints in the body. ... A joint (articulation) is the location at which two bones make contact (articulate). ...

Diagnosis

In order to diagnose Still's disease, the results of a number of common tests need to be combined. Firstly, persistent arthritis (lasting at least 6 weeks) needs to be present. Patients often have elevated white blood cell counts, suggesting they are seriously infected. Also, low counts for red blood cells (anemia) and elevated blood tests (such as sedimentation rates) for inflammation are common. However, the classic blood tests for rheumatoid arthritis and systemic lupus erythematosus are usually negative. This article discusses the medical condition. ... Sediment is any particulate matter that can be transported by fluid flow and which eventually is deposited as a layer of solid particles on the bed or bottom of a body of water or other liquid. ... Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ...

Prognosis

The fever and most of the other symptoms tend to run their course within several months. However, the arthritis can become a long-term problem as a chronic illness persisting into adulthood. Medicine In medicine, a persistent and lasting condition is said to be chronic (from Greek chronos). ... See Adult. ...

External links

• AOSD Web site
• Arthritis.org
• Adult Onset Still's Disease Discussion Board
• The AOSD Message Board
• Still's disease at medicinenet.com