Alexander Klibanov is a professor of chemistry and bioengineering at the Massachusetts Institute of Technology and a member of the National Academy of Science. He is most notable for greatly advancing the field of non-aqueous enzymology, that is, developing methods to allow enzymes to function in media such as organic solvents, rather than water. For other uses, see Chemistry (disambiguation). ... Biological engineering (also biosystems engineering and bioengineering) deals with engineering biological processes in general. ... “MIT†redirects here. ... President Harding and the National Academy of Sciences at the White House, Washington, DC, April 1921 The National Academy of Sciences (NAS) is a corporation in the United States whose members serve pro bono as advisers to the nation on science, engineering, and medicine. ... Drinking water This article focuses on water as we experience it every day. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... A solvent is a liquid that dissolves a solid, liquid, or gaseous solute, resulting in a solution. ...
AlexanderKlibanov, a chemist at the Massachusetts Institute of Technology, and his team have developed an anti-viral polymer than can be applied like paint.
Chemist AlexanderKlibanov of the Massachusetts Institute of Technology and his colleagues had already found that the bristly coating of polymers kills bacteria including Escherichia coli and Staphylococcus aureus, which can lie in wait on doorknobs or other surfaces for unsuspecting hands to pick up.
Klibanov says part of their motivation was the ongoing concern over the potential for a deadly global outbreak of flu.
Photographs of a commercial glass slide (top) and that coated with alkylated PEI (bottom) onto which aqueous suspensions of Staphylococcus aureus cells were sprayed, followed by air drying and incubation under growth agar at 37°C. Some 200 bacterial colonies are seen on the top slide, while just 4 on the bottom one.
Professor Klibanov's current research interests are in the following areas: (i) Enzymatic catalysis in nonaqueous solvents, (ii) Enzymes as stereoselective catalysts in organic synthesis, (iii) Novel microbicidal materials, and (iv) Stabilization and delivery of macromolecular pharmaceuticals (DNA and proteins).
On the mechanism of bactericidal and fungicidal activities of textiles covalently modified with alkylated polyethylenimine.
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