Allograft diseases are those in which cancerous cells are spread between individuals of the same species by physical contact. To date only two such diseases have been discovered, these are Devil facial tumour disease found in the Tasmanian Devil and canine transmissible venereal tumour which infects dogs. Image:Devil facial turmour disease. ... Binomial name Sarcophilus laniarius (Owen, 1838) Synonyms The Tasmanian Devil (Sarcophilus laniarius), also referred to simply as the devil, is a carnivorous marsupial now found only in the Australian island state of Tasmania. ...
An allograft is a transplanted organ or tissue from a genetically non-identical member of the same species.
In contrast, a transplanted organ or tissue from a genetically identical donor, i.e.
Allografts and xenografts will be recognised by the recipient's immune system as foreign and will therefore be attacked in a process termed rejection; this does not occur in autografts or true isografts (although in practice, transplants between identical twins are usually covered with immunosuppressants in case they are not 100% genetically identical).
Human skin allografts are radiated in the present invention and applied as a temporary wound dressing on a graft dome.
Histologic examination shows the frozen allograft to be well epithelialized over the allograft dermis, with the patient's dermis and epidermis underneath; while the nonviable cells of the irradiated graft have been replaced with living cells.
Skin allograft preservation by gamma irradiation has many advantages, and makes skin allograft use a possibility in areas where it is not currently available, such as small hospitals, doctors' offices, and developing countries of the world.
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