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Encyclopedia > Alloimmunization

Alloimmunity is a condition in which the body gains immunity, from another individual of the same species, against its own cells. Alloimmunity should not be confused with autoimmunity in which the body's immune system attacks its own cells without being provoked or influenced by substances or cells from another member of the same species. ... Drawing of the structure of cork as it appeared under the microscope to Robert Hook from Micrographia which is the origin of the word cell. Cells in culture, stained for keratin (red) and DNA (green). ... Autoimmunity is the failure of an organism to recognize its own constituent parts (down to the sub-molecular levels) as self, which results in an immune response against its own cells and tissues. ...


If either alloimmunity or autoimmunity is directed against red blood cells (RBCs), the direct Coombs test is positive. Human red blood cells Red blood cells are the most common type of blood cell and are the vertebrate bodys principal means of delivering oxygen to body tissues via the blood. ... Coombs test (also known as Coombs test, antiglobulin test or AGT) refers to two clinical blood tests used in haematology and immunology. ...


Alloimmunity can occur

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  Results from FactBites:
 
Alloimmunity - Wikipedia, the free encyclopedia (141 words)
Alloimmunity is a condition in which the body gains immunity, from another individual of the same species, against its own cells.
Alloimmunity should not be confused with autoimmunity in which the body's immune system attacks its own cells without being provoked or influenced by substances or cells from another member of the same species.
in the fetus after maternal antibodies have passed through the placenta into the fetus, as in haemolytic disease of the newborn and fetomaternal alloimmune thrombocytopenia.
Autoimmunity and Alloimmunity – by Pr... [#358] (2004 ISPO Symposium) (324 words)
There are evidences that many auto-immune diseases and alloimmunity are characteristic of vertebrates and that they are associated with MHC molecules.
Alloimmunity can be another by-product of evolution of the adoptive immunity which emerged under selection pressure of microbes and “latently” accumulated enormous strength.
As in the case of autoimmunity, selection pressure of alloimmunity caused the emergence of fine mechanisms for the control of immune reaction on one hand and absence of expression of MHC molecules on placental tissues, on the other – except for monomorphic and low-polymorphic MHC class Ib molecules.
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