Aloysius "Alois" Alzheimer (14 June 1864, Marktbreit, Bavaria - 19 December 1915, Breslau, now Wrocław, Poland) was a German psychiatrist and neuropathologist and a colleague of Emil Kraepelin. Alzheimer is credited with the first published case of "presenile dementia", which Kraepelin would later identify as Alzheimer's disease. June 14 is the 165th day of the year in the Gregorian calendar (166th in leap years), with 200 days remaining. ... 1864 (MDCCCLXIV) was a leap year starting on Friday (see link for calendar) of the Gregorian calendar or a leap year starting on Sunday of the 12-day-slower Julian calendar. ... Marktbreit is a city in the district of Kitzingen in the Regierungsbezirk Unterfranken in Bavaria situated at the most southern point of the Main river. ... The Free State of Bavaria  (German: Freistaat Bayern), with an area of 70,553 km² (27,241 square miles) and 12. ... December 19 is the 353rd day of the year (354th in leap years) in the Gregorian calendar. ... 1915 (MCMXV) was a common year starting on Friday (see link for calendar). ... WrocÅ‚aw ( ; German: ; Czech: ; Latin: Wratislavia or Vratislavia) is the capital of Lower Silesia in southwestern Poland, situated on the Oder River (Odra). ... Psychiatry is a branch of medicine that studies and treats mental and emotional disorders (see mental illness). ... Neuropathology is the study of diseases of the nervous system. ... Emil Kraepelin (February 15, 1856–October 7, 1926) was a German psychiatrist who attempted to create a synthesis of the hundreds of mental disorders classified by the 19th century, grouping diseases together based on classification of common patterns of symptoms, rather than by simple similarity of major symptoms in the...

Alzheimer's father served in the office of notary public in the family's hometown. Alzheimer attended Aschaffenburg, Tübingen, Berlin, and Würzburg universities. He received a medical degree at Würzburg University in 1887. In the following year, he spent five months assisting mentally ill women, before he took an office in the city mental asylum in Frankfurt am Main: the Städtische Anstalt für Irre und Epileptische (Asylum for lunatics and epileptics). Emil Sioli was the dean of that asylum (1852-1922). Another neurologist, Franz Nissl (1860-1919), began to work in that same asylum with Alzheimer, and they knew each other. Aschaffenburg is a city in Bavaria, Germany. ... Eberhard Karls University of Tübingen (German: Eberhard-Karls-Universität Tübingen) is a state-supported university located on the Neckar river, in the city of Tübingen, Baden-Württemberg, Germany. ... Berlin is the capital city and one of the sixteen states of the Federal Republic of Germany. ... [ recorded in this] The University of Würzburg is a university in Würzburg, Germany, founded in 1402. ... 1887 (MDCCCLXXXVII) is a common year starting on Saturday (click on link for calendar) of the Gregorian calendar or a common year starting on Monday of the Julian calendar. ... Frankfurt am Main [ˈfraŋkfʊrt] is the largest city in the German state of Hessen and the fifth largest city of Germany. ... 1852 was a leap year starting on Thursday (see link for calendar). ... Year 1922 (MCMXXII) was a common year starting on Sunday (link will display full calendar). ... Franz Nissl Franz Nissl (1860-1919) was born in Frankenthal in the Bavarian Palatinate, the son of Theodor Nissl and Maria Haas. ... 1860 is the leap year starting on Sunday. ... Year 1919 (MCMXIX) was a common year starting on Wednesday (link will display the full calendar). ...

Much of Alzheimer's later work on brain pathology made use of Nissl's method of silver staining of the histological sections. Alzheimer was the co-founder and co-publisher of the journal Zeitschrift für die gesamte Neurologie und Psychiatrie. He never wrote a book that he could call his own. A thin section of lung tissue stained with hematoxylin and eosin. ...

Auguste D.

In 1901, Alzheimer observed a patient at the Frankfurt Asylum named Mrs. Auguste D. The 51-year-old patient had strange behavioral symptoms, including a loss of short-term memory. This patient would become his obsession over the coming years. In April 1906, Mrs. D. died and Alzheimer had the patient records and the brain sent to Munich where he was working at Kraepelin's lab. Together with two Italian physicians, he would use the staining techniques to identify amyloid plaques and neurofibrilary tangles. A speech given on 3 November 1906 would be the first time the pathology and the clinical symptoms of presenile dementia would be presented together.^[1] Image File history File links Download high-resolution version (702x710, 115 KB) Description: Auguste D. from Marktbreit, Germany - Alois Alzheimers patient in 1906 Uploaded by: --Immanuel Giel 09:25, 24 January 2007 (UTC) File links The following pages on the English Wikipedia link to this file (pages on other projects... Image File history File links Download high-resolution version (702x710, 115 KB) Description: Auguste D. from Marktbreit, Germany - Alois Alzheimers patient in 1906 Uploaded by: --Immanuel Giel 09:25, 24 January 2007 (UTC) File links The following pages on the English Wikipedia link to this file (pages on other projects... 1901 (MCMI) was a common year starting on Tuesday (see link for calendar) of the Gregorian calendar (or a common year starting on Wednesday of the 13-day-slower Julian calendar). ... Amyloid describes various types of protein aggregations that share specific traits when examined microscopically. ... November 3 is the 307th day of the year (308th in leap years) in the Gregorian Calendar, with 58 days remaining. ... 1906 (MCMVI) was a common year starting on Monday (see link for calendar). ...

Since German was the common language of science and especially of Psychology of the time, Kraepelin's use of Alzheimer's disease in a textbook would make the name famous. By 1911, the disease was being used by European physicians to diagnose patients in the US. ^[1]

In mid-December 1915, Alzheimer fell ill on the train on the way to the University of Breslau, where he had been appointed professor of psychiatry in 1912. Most probably he had a streptococcal infection and subsequent rheumatic fever and kidney failure. He died of heart failure at the age of 51 in Breslau. Species S. agalactiae S. bovis S. faecalis S. pneumoniae S. pyogenes S. suis S. viridans S. salivarius Streptococcus is a genus of spherical, Gram-positive bacteria of the phylum Firmicutes. ... Rheumatic fever is an inflammatory disease which may develop after a Group A streptococcal infection (such as strep throat or scarlet fever) and can involve the heart, joints, skin, and brain. ... Renal failure is when the kidneys fail to function properly. ... Wrocław. ...

External links

• Who Named It? - Alois Alzheimer
• Alois Alzheimer's Biography, International Brain Research Organization
• Ludwig-Maximilians-University Munich, Laboratory for Neurodegenerative Disease Research - Prof. Dr. Christian Haass

References

1. ^ ^{a b} Maurer K., Maurer U. (2003). Alzheimer: The Life of a Physician and Career of a Disease. New York: Columbia University Press. ISBN 0-231-11896-1.