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Encyclopedia > Alprostadil
Alprostadil chemical structure
Alprostadil
Systematic (IUPAC) name
7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)- 5-oxo-cyclopentyl] heptanoic acid
Identifiers
CAS number 745-65-3
ATC code C01EA01 G04BE01
PubChem 149351
DrugBank APRD00785
Chemical data
Formula C20H34O5
Mol. weight 354.481 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

? IUPAC nomenclature is a systematic way of naming organic chemical compounds. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... PubChem is a database of chemical molecules . ... DrugBank is a database available at the University of Alberta that provides information about thousands of products. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεταβολισμος (metabolismos)) is the biochemical modification of chemical compounds in living organisms anggjgjhnd cell (b). ... The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ... Excretion is the biological process by which an organism chemically separates waste products from its body. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status
Routes  ?

Alprostadil is a prostaglandin analogue used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Chemical structure of prostaglandin E1 (PGE1). ... Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. ...


It is also used in maintaining a patent ductus arteriosus in the fetus. This is primarily useful when there is threat of premature closure of the ductus arteriosus. Patent ductus arteriosus (PDA) is a congenital heart defect wherein a childs ductus arteriosus fails to close after birth. ... Fetus at eight weeks Foetus redirects here. ...



Urologicals (G04) edit

Acidifiers: Ammonium chloride, Calcium chloride A section of the Anatomical Therapeutic Chemical Classification System. ... These are inorganic chemicals used to produce or become acid. ... Ammonium chloride or Sal Ammoniac (chemically ammonium chloride (NH4Cl); also nushadir salt, zalmiak, sal armagnac, sal armoniac, and salt armoniack) is, in its pure form, a clear white water-soluble crystalline salt with a biting taste. ... R-phrases S-phrases , , RTECS number EV9800000, anhydrous EV9810000, dihydrate EV9830000, hexahydrate Supplementary data page Structure & properties n, εr, etc. ...


Urinary antispasmodics: Darifenacin, Emepronium, Flavoxate, Meladrazine, Oxybutynin, Propiverine, Solifenacin, Terodiline, Tolterodine, Trospium The urinary system is a system of organs, tubes, muscles, and nerves that work together to create, store, and carry, urine. ... An antispasmodic is a drug that suppresses smooth muscle contraction, especially in tubular organs. ... Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. ... Flavoxate is an anticholinergic with antimuscarinic effects. ... Oxybutynin is an anti-cholinergenic pharmaceutical used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination. ... Tolterodine is an antimuscarinic drug that is used to treat incontinence. ...


Drugs used in erectile dysfunction: Alprostadil, Apomorphine, Moxisylyte, Papaverine, Phentolamine, Sildenafil, Tadalafil, Vardenafil, Yohimbin Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. ... Apomorphine is a type of dopaminergic agonist, a morphine derivative which primarily affects the hypothalamic region of the brain. ... Papaverine is an opium alkaloid (opiate) used intravenously in the treatment of erectile dysfunction. ... Phentolamine is a competitive nonselective alpha adrenergic receptor antagonist. ... Sildenafil citrate, sold under the names Viagra, Revatio and generically under various other names, is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. ... Tadalafil is a drug used to treat male erectile dysfunction (impotence). ... Vardenafil (Levitra) is a PDE5 inhibitor used in the treatment of erectile dysfunction. ...


Other urologicals: Acetohydroxamic acid, Collagen, Dimethyl sulfoxide, Magnesium hydroxide, Phenazopyridine, Phenyl salicylate, Succinimide Acetohydroxamic acid is a urological drug. ... Tropocollagen triple helix. ... Dimethyl sulfoxide (DMSO, molecular formula C2H6OS), also known as methyl sulfoxide, dimethyl sulphoxide, dimethylsulfoxide, methylsulfinylmethane or sulfinylbismethane, is a sulfur-containing organic compound. ... Magnesium hydroxide, Mg(OH)2, otherwise known as milk of magnesia, is commonly used as an antacid or a laxative. ... Phenazopyridine is a chemical which, when secreted into the urine, has a specifical local analgesic effect. ... Succinimides are drugs that can be used as anticonvulsants. ...


Drugs used in benign prostatic hypertrophy: Alfuzosin, Dutasteride, Finasteride, Mepartricin, Tamsulosin, Terazosin, Pygeum africanum ยท Serenoa repens Benign prostatic hyperplasia (BPH) is the increase in size of the prostate in middle_aged and elderly men. ... Alfuzosin ((R,S)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl) methylamino] propyl] tetrahydro-2-furancarboxamide, provided as the hydrochloride salt) is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). ... Dutasteride inhibits the conversion of testosterone into dihydrotestosterone. ... Finasteride (marketed as Proscar®, Propecia®, Fincar®, Finpecia®, Finax®, Finast®, Finara®, Prosteride®) is an antiandrogen which acts by inhibiting 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone. ... Tamsulosin is the generic name for a medicine (usually sold as Flomax), which is commonly used as an alpha blocker, particularly to treat the syptoms of benign prostatic hypertrophy (BPH)—enlargement of the male prostate gland. ... Terazosin (Hytrin) is an alpha blocker used for treatment of symptoms of prostate enlargement (BPH). ... Binomial name Serenoa repens Hooker Saw Palmetto, Serenoa repens, is the sole species currently classified in the genus Serenoa. ...



 

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