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Alveolar Soft Parts Sarcoma (6748 words) |
 | Cytogenetic abnormalities of alveolar soft-part sarcomas using interphase fluorescent in situ hybridization: trisomy for chromosome 7 and monosomy for chromosomes 8 and 18 seem to be characteristic of the tumor. |
| Alveolar soft-part sarcoma (ASPS) is a rare tumor of uncertain histogenesis, mainly localized in the extremities and less frequently found in the head, neck and trunk. |
| Alveolar soft-part sarcoma is a rare soft tissue malignant tumor that commonly arises in skeletal muscles or musculofascial planes in children and young adults. |
| Mechanisms Associated with Human Alveolar Macrophage Stimulation by Particulates (4214 words) |
| The alveolar macrophage is therefore hypothesized to play a central role in the development of particulate-induced pulmonary fibrosis (4-6) through the inappropriate release of effector molecules with bioactivity for lung cells in response to fibrogenic particulates. |
| Alveolar macrophages from animals (7,8) and healthy human volunteers (9) exposed to fibrogenic particulates in vitro release factors that enhance fibroblast growth. |
| Whether the release of these factors by alveolar macrophages exposed to particulates in vivo is a result of their direct interaction with the particulates, an indirect result of the interaction of the particulates with other lung cell types, or both, is not known. |
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