 | | Cefazolin | | Systematic (IUPAC) name | | 3-[(5-methyl-1,3,4-thiadiazol-2-yl) sulfanylmethyl]-8-oxo-7- ([2-(tetrazol-1-yl)acetyl]amino)- 5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate | | Identifiers | | CAS number | ? | | ATC code | J01DB04 | | PubChem | 2617 | | Chemical data | | Formula | C14H13N8O4S3- | | Mol. weight | 453.503 | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | ? | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? IUPAC nomenclature is a systematic way of naming organic chemical compounds. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules . ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Metabolism (from Greek μεταβολισμός metabolismos) is the biochemical modification of chemical compounds in living organisms and cells. ...
The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the biological process by which an organism chemically separates waste products from its body. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
| | Legal status | Unscheduled The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
| | Routes | I.V. | Cefazolin, also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
The cephalosporins, are a class of β-lactam antibiotics. ...
Staphylococcus aureus - Antibiotics Test plate. ...
The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein). An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ...
Indications
Cefazolin is mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is effective only against infections caused by staphylococci and streptococci species of bacteria. These organisms are common on normal human skin. Resistance to cefazolin is seen in several species of bacteria. Species S. aureus S. caprae S. epidermidis S. haemolyticus S. hominis S. lugdunensis S. saprophyticus S. warneri S. xylosus Staphylococcus (in Greek staphyle means bunch of grapes and coccos means granule) is a genus of gram-positive bacteria. ...
Streptococcus, a genus of spherical, Gram-positive bacteria of the phylum Firmicutes. ...
Subgroups Actinobacteria Aquificae Bacteroidetes/Chlorobi Chlamydiae/Verrucomicrobia Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Nitrospirae Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Bacteria (singular: bacterium) are microscopic, unicellular organisms. ...
Side effects Side effects from cefazolin are not common. Possible side effect includes: - diarrhea
- stomach pain
- upset stomach
- vomiting
Cefazolin is marketed under the following brand names: Ancef®, Cefacidal®, Cefamezin®, Cefrina®, Elzogram®, Gramaxin®, Kefazol®, Kefol®, Kefzol®, Kefzolan®, Kezolin®, Novaporin®, and Zolicef®
External links - MedlinePlus Drug Information: Cefazolin Sodium Injection.
- Eli Lilly Cafazolin Sodium Material Safety Data Sheet.
- Link page to external chemical sources.
| Cephalosporin Antibiotics (J01D) edit | | | First Generation: | Cefacetrile, Cefadroxil, Cefalexin, Cephaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole The cephalosporins, are a class of β-lactam antibiotics. ...
Staphylococcus aureus - Antibiotics Test plate. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Cefacetrile (also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in G+ and G- bacterial infections. ...
Cefadroxil is a broadspectrum antibiotic effective on both bactria GRAM +ve and GRAM -ve bactria. ...
Cephalexin structure (racemic) Cefalexin (previously also British Approved Name Cephalexin) is a drug that is a member of the cephalosporin class of antibiotics. ...
Cephaloglycin is a first generation cephalosporin antibiotic. ...
Cefalotin (INN) (IPA: ) or cephalothin (USAN) (IPA: ) is a first-generation cephalosporin antibiotic. ...
Cefapirin (or cephapirin) is a first-generation cephalosporin antibiotic. ...
Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic. ...
| | Second Generation: | Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam Cefaclor (brand name Raniclor®) is a 2nd generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. ...
Ceforanide is a second-generation cephalosporin antibiotic Crowle A, Sbarbaro J, May M (1988). ...
Cefotiam is a second-generation cephalosporin antibiotic. ...
Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin antibiotic. ...
Cefuroxime is an cephalosporin antibiotic that has been widely available in the USA since 1977. ...
| | Third Generation: | Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef Cefdinir is a semi-synthetic antibiotic in the third generation of the cephalosporin family of antibiotics. ...
Cefixime is an oral third generation cephalosporin antibiotic. ...
Cefmenoxime is a third-generation cephalosporin antibiotic. ...
Cefotaxime is a third generation intravenous cephalosporin antibiotic. ...
Cefpiramide is a third-generation cephalosporin antibiotic. ...
Cefpodoxime is an oral third generation cephalosporin antibiotic. ...
Ceftazidime is an antibiotic which eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. ...
Ceftriaxone (trade name Rocephin®) is a third-generation cephalosporin antibiotic. ...
| | Fourth Generation: | Cefclidine, Cefepime, Cefetecol Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome This article needs to be cleaned up to conform to a higher standard of quality. ...
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