Andronicus Palaeologus ( 1403 - 1429 ) despot of Thessalonica 1408-1423 is son of Byzantine emperor Manuel II . The White Tower The Arch of Galerius Map showing the Thessaloníki prefecture Thessaloníki (Θεσσαλονίκη) is the second-largest city of Greece and is the principal city and the capital of the Greek region of Macedonia. ... The Byzantine Empire around year 1400. ...
In childhood he is surviving sickness which has killed his brothers Michael and Constantin older, but he has never recovered in full staying always man of poor health. When he has been only 5 years old father has made him despot of Thessalonica when his cousin old despot John VII Palaeologus has died. John VII (1370-1408), surnamed Palaeologus, Byzantine emperor, grandson of John V, initially ruled for only six months in 1390. ...
After crowning of John VIII on crown heir position in 1421 Byzantine empire has started war against Turks. Not long after that Thessalonica had been besieged. Now under siege Andronicus has lost calm and started international talks for giving city to Venetia. In the end that has happened. Venetia military forces has entered city against population wishes in 1423. This move is reason for first long Venetia-Turkish war. Turkish soldiers has entered Thessalonica in 1430.
Less of one year after giving city to Venetia Andronicus has entered monastery where he has died in 1429.
Bibliography
Joseph von Hammer "Geschichte des Osmanischen Reiches"
Edward Gibbon "The History of Decline and Fall of Roman Empire"
Manuel II was the father of John VIII Palaeologus and Constantine XI, the last Byzantine emperor (Constantine XI Palaeologus), as well as the despots of Morea Thomas and Demetrius Palaeologus.
Andronicus II married firstly Anna of Hungary and fathered Michael Palaeologus, who predeceased his father but was a co-regent, as such sometimes numbered the ninth.
Andronicus III married firstly a princess of Brunswick, who died without surviving issue, and secondly Anne of Savoy who was descended from Baldwin I of Constantinople.