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Encyclopedia > Anemia, Sideroblastic

Sideroblastic anemia is caused by the abnormal production of red blood cells as part of myelodysplastic syndrome, which can evolve into hematological malignancies (especially acute myelogenous leukemia). Human red blood cells Red blood cells are the most common type of blood cell and are the vertebrate bodys principal means of delivering oxygen from the lungs or gills to body tissues via the blood. ... Although hematological malignancies are a form of cancer, they are generally treated by specialists in hematology, although in many hospitals oncology specialists also manage these diseases. ... Acute myelogenous leukemia (AML), also known as acute myeloid leukemia, is a cancer of the myeloid line of blood cells. ...


Diagnosis

Ringed sideroblasts are seen in the bone marrow


Laboratory findings=

  • increased ferritin levels
  • increased total iron binding capacity

See also


  Results from FactBites:
 
Anemia - Wikipedia, the free encyclopedia (2343 words)
In older patients, iron deficiency anemia is often due to bleeding lesions of the gastrointestinal tract; fecal occult blood testing, upper endoscopy and lower endoscopy are often performed to identify bleeding lesions, which can be malignant.
Megaloblastic anemia due to a deficiency of either vitamin B12 or folic acid (or both) due either to inadequate intake or insufficient absorption.
The cause of megaloblastic anemia is primarily a failure of DNA synthesis with preserved RNA synthesis, which result in restricted cell division of the progenitor cells.
SIDEROBLASTIC ANEMIAS (6908 words)
Vacuoles in normoblasts and myeloid precursors are prominent in the sideroblastic anemia of Pearson's syndrome.
Sideroblastic anemia remains in the differential diagnosis of patients with iron deficiency and anemia that is refractory to iron replacement.
X-linked sideroblastic anemia and ataxia: linkage to phosphoglycerate kinase at Xq13.
  More results at FactBites »


 
 

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