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An aneurysmal bone cyst is an expansile osteolytic lesion with a thin wall, containing blood-filled cystic cavities. The term aneurysmal is derived from its radiographic appearance. For other uses, see Bone (disambiguation), including Bones which redirects here. ...
A cyst is a closed sac having a distinct membrane and developing abnormally in a cavity or structure of the body. ...
A lesion is a non-specific term referring to abnormal tissue in the body. ...
Radiography is the creation of radiographs, photographs made by exposing a photographic film or other image receptor to X-rays. ...
Causes
Trauma is considered the initiating factor in the development of some cysts, in documented cases involving an acute fracture. Local alterations in the blood flow are related to obstructions that are important in the development of an aneurysmal bone cyst. A cyst is a closed sac having a distinct membrane and developing abnormally in a cavity or structure of the body. ...
The lesion generally arises in a preexisting bone tumor, this is because of the abnormal bones changes in hemodynamics. An aneurysmal bone cyst can arise from a preexisting chondroblastoma, a chondromyxoid fibroma, an osteoblastoma, a giant cell tumor, or fibrous dysplasia. A giant cell tumor is the most common cause, occurring in 19% to 39% of cases. Less frequently, it results from some malignant tumors, such as osteosarcoma, chondrosarcoma, and hemangioendothelioma. Tumor (American English) or tumour (British English) originally means swelling, and is sometimes still used with that meaning. ...
Hemodynamics is concerned with the forces generated by the heart and the motion of blood through the cardiovascular system. ...
Fibrous Dysplasia is a disease that causes growths or lesions in one or more bones of the human body. ...
In medicine, malignant is a clinical term that is used to describe a clinical course that progresses rapidly to death. ...
Osteosarcoma is a common primary bone cancer. ...
A chondrosarcoma is a cancer of the cartilage. ...
Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign or malignant in their activity. ...
Effects Aneurysmal bone cysts may be intraosseous, staying inside of the bone marrow. Or they may be extraosseous, developing on the surface of the bone, and extending into the marrow. Intraosseous infusion is the process of injection directly into the marrow of the bone. ...
Phases 1. Initial phase of osteolysis. Dissolution or degeneration of bone tissue through disease. ...
2. Active growth phase, characterized by destruction of bone tissue.
3. Stable stage, where a formation of a bony shell and interal bony septae produce its soap bubble appearance.
4. Healing phase where the cyst eventually heals into an irregular dense bony mass.
Occurrences Aneurysmal bone cysts are more common in females than males. Most of these occur between the ages of 10-30, with about 75% of incidences happening to patients under the age of 20.
Anatomy The tumor can have an occurrence anywhere that there is bone. Approximate percentages by sites are as shown.
Symptoms The afflicted may have relatively small amounts of pain that will quickly increase in severity over a time period of 6-12 weeks. The skin temperature around the bone may increase, a bony swelling may be evident, and movement may be restricted in adjacent joints.
Spinal lesions may cause quadriplegia and patients with skull lesions may have headaches. A lesion is a non-specific term referring to abnormal tissue in the body. ...
Quadriplegia, also known as tetraplegia, is a symptom in which a human experiences paralysis of all four limbs, although not necessarily total paralysis. ...
See also Giant cell tumor of bone
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