Angiopathy is a disease of the blood vessels (arteries, veins, and capillaries) that occurs when someone has diabetes for a long time. There are two types of angiopathy: macroangiopathy and microangiopathy. In macroangiopathy, fat and blood clots build up in the large blood vessels, stick to the vessel walls, and block the flow of blood. In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood through the body. Then the cells, for example, the ones in the center of the eye, do not get enough blood and may be damaged.
Senile cerebral amyloid angiopathy (CAA) is neurological condition in which amyloid protein is deposited onto the walls of the arteries of the brain.
Senile cerebral amyloid angiopathy is a cause of lobar intracerebral hemorrhage (bleeding in a localized area of the brain, a form of stroke) in the elderly.
Senile cerebral amyloid angiopathy is not specifically diagnosed until after death, when a postmortem biopsy reveals amyloid deposits in the blood vessels of the brain.
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