NationMaster - Encyclopedia: Anistreplase

Anistreplase is a thrombolytic drug. It converts plasminogen to plasmin, which in turn degrades fibrin (blood clots) to fibrin split products. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Thrombolysis is the breakdown (lysis) by pharmacological means, of blood clots. ... Plasmin is an important degrading enzyme (EC 3. ... Plasmin is an important degrading enzyme (EC 3. ... A thrombus is the final product of blood coagulation, through the aggregation of platelets and the activation of the humoral coagulation system. ...

Categories: Fibrinolytic system | Pharmacology stubs Thrombolytic drugs are used in medicine to dissolve blood clots in a procedure termed thrombolysis. ... An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting. ... An antiplatelet drug is a member of a class of pharmaceuticals that decreases platelet aggregation and inhibits thrombus formation. ... A section of the Anatomical Therapeutic Chemical Classification System. ... Vitamin K1 (phylloquinone). ... Acenocoumarol is a anticoagulant that functions as a vitamin K antagonist (like warfarin). ... Please wikify (format) this article as suggested in the Guide to layout and the Manual of Style. ... Dicumarol (or Dicoumarol) is a anticoagulant that functions by as a Vitamin K antagonist (similar to warfarin). ... Phenprocoumon is an anticoagulant, functioning as a Vitamin K antagonist. ... Phenindione is an anticoagulant which functions as a Vitamin K antagonist. ... Warfarin (also known under the brand names of Coumadin, Jantoven, Marevan, and Waran) is an anticoagulant medication that is administered orally or, very rarely, by injection. ... Antithrombin is a small molecule that inactivates several enzymes of the coagulation system. ... Dalteparin is a low molecular weight heparin. ... Danaparoid sodium (OrgaranÂ®) is an anticoagulant that works by inhibiting thrombin. ... Enoxaparin is a low molecular weight heparin manufactured by Sanofi-Aventis. ... Heparin, a highly sulfated glycosaminoglycan is widely used as an injectable anticoagulant and has the highest negative charge density of any known biological molecule. ... In medicine, low molecular weight heparin (LMWH) is a class of medication used as an anticoagulant in diseases that feature thrombosis, as well as for prophylaxis in situations that lead to a high risk of thrombosis. ... Abciximab (previously known as c7E3 Fab), distributed by Eli Lilly under the trade name ReoPro®, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. ... A very old bottle of Aspirin Aspirin or acetylsalicylic acid is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. ... Clopidogrel (IPA: ) is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease. ... Dipyridamole is a drug that inhibits platelet aggregation and causes vasodilation. ... Eptifibatide (IntegrilinÂ®, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an anti-coagulant that selectively blocks the platelet glycoprotein IIb/IIIa receptor. ... iloprost, an inhalation solution, is sold under the name VentavisÂ® and is used to treat pulmonary arterial hypertension (PAH). ... Prasugrel is a novel platelet inhibitor developed by Sankyo and produced by Ube and currently under clinical development in cooperation with Eli Lilly for acute coronary syndromes planned for PCI. Categories: Biochemistry stubs | Pharmacology stubs ... Prostacyclin is a member of the family of lipid molecules known as eicosanoids. ... Ticlopidine is a drug used for its antiplatelet action. ... Tirofiban (INN, trade name AggrastatÂ®) is an anticoagulant drug. ... Trepostinil is a synthetic analogue of prostacyclin, used to treat pulmonary hypertension. ... In blood coagulation, tissue plasminogen activator (tPA) is an enzyme (EC 3. ... // Basic Chemical, Pharmacological, and Marketing Information Ancrod (also known under its former brand name ArwinÂ® and recently ViprinexÂ®) is an anticoagulant with a triple mode of action. ... Drotrecogin alpha (activated) (XigrisÂ®, marketed by Eli Lilly) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties. ... // Basic Information Fibrinolysin is an enzyme derived from plasma of bovine origin or extracted from cultures of certain bacteria. ... Protein C is a major physiological anticoagulant. ... Reteplase (RetavaseÂ®) is a thrombolytic drug, used to treat heart attacks by breaking up the clots that cause them. ... Streptokinase is an extracellular metallo-enzyme produced by beta-haemolytic streptococcus and is used as an effective and cheap clot-dissolving medication in some cases of myocardial infarction (heart attack) and pulmonary embolism. ... Tenecteplase is an enzyme used as a thrombolytic drug. ... Urokinase, also called urokinase-type Plasminogen Activator (uPA) is an enzyme (EC 3. ... Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin. ... Argatroban is a small molecule direct thrombin inhibitor. ... Basic Chemical and Pharmacological Properties Bivalirudin is an anticoagulant and acts as direct thrombin antagonist. ... Dabigatran is an anticoagulant from the class of the direct thrombin inhibitors. ... Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property. ... Hirudin is a naturally ocurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property. ... Lepirudin is an anticoagulant which functions as a direct thrombin inhibitor. ... Ximelagatran (Exanta®, H 376/95) is an anticoagulant that has been investigated extensively but is awaiting approval by the Food and Drug Administration (FDA). ... Ximelagatran (Exanta®, H 376/95) is an anticoagulant that has been investigated extensively but is awaiting approval by the Food and Drug Administration (FDA). ... Defibrotide is a deoxyribonucleic acid derivative (single stranded) derived from cow lung or porcine mucosa. ... Dermatan sulfate is a glycosaminoglycan, formerly called a mucopolysaccharide, found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs. ... Fondaparinux (Arixtra) is an anticoagulant medication. ... Rivaroxaban (also known as BAY 59-7939) is an oral anticoagulant under development by Bayer. ... An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting. ... Chemical strucutre of citric acid. ... EDTA is a widely-used acronym for the chemical compound ethylenediamine tetraacetic acid (and many other names, see table). ... An oxalate (called also: ethanedioate) is a salt or ester of oxalic acid. ...