In literature, the antagonist is that against which the main character or protagonist contends. [1] An antagonist is often a Villain, but may be a force of nature, set of circumstances, an animal, or other force that is in conflict with the protagonist.[2] An example of an antagonist is Lord Voldemort in the Harry Potter Series of books by J.K. Rowling. Look up antagonist, antagonism in Wiktionary, the free dictionary. ... A protagonist is the main figure of a piece of literature or drama and has the main part or role. ... Bad guy redirects here. ... Lord Voldemort (IPA: [1][2]) is a fictional character and the primary antagonist in the Harry Potter novel series written by British author J. K. Rowling. ... This article is about the Harry Potter series of novels. ... Joanne Rowling OBE (born July 31, 1965 in Chipping Sodbury, South Gloucestershire), commonly known as J.K. Rowling (pronunciation: roll-ing; her former students used to joke with her name calling her the Rolling Stone), is a British fiction writer. ...
Bad guy redirects here. ... Flag Ship from the video game Gorf A boss is an enemy-based challenge in video games that, once encountered, stops the games progression until the player is able either to surmount the enemy or is thwarted by it. ... A protagonist is the main figure of a piece of literature or drama and has the main part or role. ... ‹ The template below (Rescue) is being considered for deletion. ... In film, television, or literature, a false protagonist is a technique for making a scene more jarring or a character more notable. ... Antagonists will block the binding of an agonist at a receptor molecule, inhibiting the signal produced by a receptor-agonist coupling. ...
References
^ About.com, Literature: Contemporary "Antagonist." Online. October 18, 2007.
^ The Elements of Literature. Online. October 18, 2007.
The present invention involves methods of inducing opiate-receptor antagonistic activity in a patient suffering from ischemic or traumatic central nervous system injury by administering to said patient an effective amount of an opiate-receptor antagonist having enhanced activity at the kappa-opiate receptor suitable to permit the induction of opiate-receptor antogonistic activity.
A method of inducing kappa-opiate-receptor antagonistic activity in a patient suffering from ischemic or traumatic central nervous system injury which comprises administering to said patient an effective amount of a kappa-opiate-receptor antagonist suitable to permit the induction of kappa-opiate receptor antagonistic activity.
The present invention provides a method of inducing opiate-receptor antagonistic activity in a patient suffering from ischemic or traumatic central nervous system injury which comprises administering to said patient an effective amount of an opiate-receptor antagonist having enhanced activity at the kappa-opiate receptor suitable to permit the induction of opiate-receptor antagonistic activity.
As the concentration of antagonist is increased, the binding of the agonist is progressively inhibited, resulting in a decrease in the physiological response.
A competitive antagonist, therefore, shifts the dose-response relationship for the agonist to the right, so that an increased concentration of the agonist in the presence of a competitive antagonist is required to produce the same biological response observed in the absence of the antagonist.
In this case, the binding of the antagonist to the receptor (its affinity) may be so strong that the receptor is unavailable for binding by the agonist.
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