Antibiotic sensitivity is the microbial susceptibility of microorganisms such as bacteria to antibiotics. Ideal antibiotic therapy is based on determination of the aetiological agent and its relevant antibiotic sensitivity. Empiric treatment is often started before laboratory microbiological reports are available when treatment should not be delayed due to the seriousness of the disease. Jump to: navigation, search A microorganism or microbe is an organism that is so small that it is microscopic (invisible to the naked eye). ... Jump to: navigation, search Phyla/Divisions Actinobacteria Aquificae Bacteroidetes/Chlorobi Chlamydiae/Verrucomicrobia Chloroflexi Chrysiogenetes Cyanobacteria Deferribacteres Deinococcus-Thermus Dictyoglomi Fibrobacteres/Acidobacteria Firmicutes Fusobacteria Gemmatimonadetes Nitrospirae Planctomycetes Proteobacteria Spirochaetes Thermodesulfobacteria Thermomicrobia Thermotogae Bacteria (singular, bacterium) are a major group of living organisms. ... An antibiotic is a drug that kills or slows the growth of bacteria. ...
The effectiveness of individual antibiotics varies with the location of the infection, the ability of the antibiotic to reach the site of infection, and the ability of the bacteria to resist or inactivate the antibiotic. Some antibiotics actually kill the bacteria (bactericidal), whereas others merely prevent the bacteria from multiplying (bacteriostatic) so that the host's immune system can overcome them.
Antibiotics that are active against the bacterial cytoplasmic membrane are polymyxin B and E (colistin).
Antibiotics that block transcription in bacteria are actinomycin D and rifampin.
Antibiotics that block translation in bacteria by binding to the 30S ribosome are the aminoglycosides, nitrofurans, spectinomycin and the tetracyclines.