FACTOID # 170: Apparently, the Federated States of Micronesia is the place to leave - and Afghanistan is the place to go.
 
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Encyclopedia > Anticarcinogen

An anticarcinogen is any chemical which reduces the occurrence of cancers, reduces the severity of cancers that do occur, or acts against cancers that do occur, based on evidence from in vitro studies, animal models, epidemiological studies and/or clinical studies. Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues, either by direct growth into adjacent tissue through invasion or by implantation into distant sites by metastasis. ... Wiktionary has a definition of: In vitro In vitro (Latin: within glass) means within a test tube, or, more generally, outside a living organism or cell. ... Epidemiology (Greek epi = upon, among; demos = people, district; logos = word, discourse), defined literally, is the study of epidemics in humans. ... In medicine, a clinical trial (synonyms: clinical studies, research protocols, medical research) is a research study. ...


Preventative anticarcinogens act by enhancing an organism's natural defenses against cancer, by deactivating cancer causing agents or by blocking the mechanisms by which cancer causing agents act (such as free radical damage to DNA). In chemistry free radicals are uncharged atomic or molecular species with unpaired electrons or an otherwise open shell configuration. ... The general structure of a section of DNA Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the biological development of a cellular form of life or a virus. ...


Anticarcinoma agents participate in the selective destruction of cancer cells, or inhibit the growth and proliferation of cancer cells.


Interest in preventative anticarcinogens is motivated primarily by the principle that it is preferable to prevent disease where possible, and that positive actions can be effective as well as negative ones (such as reducing exposure to known carcinogens). Anticarcinoma agents that do not have significant negative side effects have a similar potential role, by reducing the seriousness of any cancers that do occur. In pathology, a carcinogen is any substance or agent that promotes cancer. ...


Known anticarcinogens

There is epidemiological evidence that a diet rich in antioxidant vitamins and flavonoids is anticarcinogenic. Interest in many popular nutritional supplements, including essential antioxidant nutrients such as selenium compounds and hormones such as melatonin and DHEA, is partly motivated by evidence that these have significant anticarcinogenic effects in appropriate quantities. Retinol (Vitamin A) Vitamins are nutrients required in very small amounts for essential metabolic reactions in the body [1]. The term vitamin does not encompass other essential nutrients such as dietary minerals, essential fatty acids, or essential amino acids. ... Molecular structure of flavone The term flavonoid refers to a class of plant secondary metabolites based around a phenylbenzopyrone structure. ... Se redirects here. ... Melatonin, 5-methoxy-N-acetyltryptamine, is a hormone found in all living creatures from algae[1] to humans, at levels that vary in a diurnal cycle. ... Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. ...


  Results from FactBites:
 
Anticarcinogenic Responses in Rodent Cancer Bioassays are (1251 words)
The number of chemicals with at least one "anticarcinogenic" response changes from the published (22.8)/(25)/(47.8)/(44.6)% to (21.8)/(22.8)/(42.3)/(41.7)% after the correction for the reduced denominator and dose trend test.
This apparent anticarcinogenic response could be spurious for either one of two reasons.
When we restrict the analysis to those for which NTP assigned a number we increase the percentage of "anticarcinogenic" chemicals and the conclusions of the papers are very slightly enhanced.
The Antimutagenic and Anticarcinogenic Effects of Wheat Grains (1133 words)
Cancer is the second leading cause of death in the United States, and colorectal cancer is the third most common cancer diagnosed in Americans.
Besides dietary fiber, whole grains are also rich sources of a wide range of phytochemicals with probable anticarcinogenic properties.
Therefore, it may be warranted in future studies to isolate and purify individual antimutagens released during aqueous incubation of the cereal grains and then test these compounds in rats using doses of HCA mutagens relevant to human exposure.
  More results at FactBites »


 
 

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