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Formulations and methods of reducing toxicity of antineoplastic agents - United States Patent 6,057,361 (12927 words) |
 | Antineoplastic antibiotics are one of the oldest classes of oncology drugs (Actinomycin was introduced into the clinic in 1954), and are still widely used in the treatment of pediatric neoplasms (Actinomycin), testicular neoplasms (Bleomycin), and any of a number of other solid tumors. |
| The preferred dosage of many antineoplastic agents is a variable, and is based upon the type of tumor, other drugs included in the therapeutic regimen, height of the patient, weight of the patient, age of the patient, and in some cases, the gender of the patient. |
| As with most antineoplastic agents, where the exact mechanism(s) of action is not a certainty, the mechanism(s) of protection by which the formula I compounds reduce the toxicity of the antineoplastic agents is not as yet fully understood. |
| Antineoplastic Agents: Introduction - The Merck Veterinary Manual (2156 words) |
| Antineoplastic chemotherapy is an important component of small animal practice and is routinely used for selected tumors of horses and cattle. |
| Antineoplastic agents can be classified according to a number of schemes relative to effects at different stages of the cell cycle. |
| The decision to use antineoplastic chemotherapy depends on the type of tumor to be treated, the stage of malignancy, the condition of the animal, and financial constraints. |
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