Apamea is located on the right bank of the Orontes River, about 55 km to the northwest of Hama, Syria, overlooking the Ghab valley. Previously known as Pharmake, it was reestablished by Seleucus I Nicator in 300 BC, who named it after his Bactrian wife, Apame. Located at a strategic crossroads for Eastern commerce, the city flourished to the extent that its population eventually numbered half a million. It was conquered by Pompey in 64 BCE and annexed in the Roman Empire. The Orontes or ‘Asi is a river of Lebanon and Syria. ... Seleucus I (surnamed for later generations Nicator, in Greek:Σέλευκος Νικάτωρ) (c. ... Centuries: 4th century BC - 3rd century BC - 2nd century BC Decades: 350s BC 340s BC 330s BC 320s BC 310s BC - 300s BC - 290s BC 280s BC 270s BC 260s BC 250s BC Years: 305 BC 304 BC 303 BC 302 BC 301 BC - 300 BC - 299 BC 298 BC... Bactria (Bactriana) was the ancient Greek name of the country between the range of the Hindu Kush (Caucasus Indicus) and the Amu Darya (Oxus), with the capital Bactra (now Balkh) in Afghanistan. ... This article refers to the General of the Roman republic. ... Centuries: 2nd century BC - 1st century BC - 1st century Decades: 110s BC 100s BC 90s BC 80s BC 70s BC - 60s BC - 50s BC 40s BC 30s BC 20s BC 10s BC Years: 69 BC 68 BC 67 BC 66 BC 65 BC 64 BC 63 BC 62 BC 61... The Roman Empire is the term conventionally used to describe the Ancient Roman polity in the centuries following its reorganization under the leadership of Octavian (better known as Caesar Augustus). ...