The Concordat of 1801 assigned as the boundaries of the Archdiocese of Lyons the Departments of the Rhône, the Loire, and the Ain and as suffragans the Dioceses of Mende, Grenoble, and Chambéry.
In 1822 the Department of Ain was separated from the Archdiocese of Lyons to form the Diocese of Belley; the title of the suppressed church of Embrun was transferred to the Archdiocese of Aix, and the Archdiocese of Lyons and Vienne had henceforth as suffragans Langres, Autun, Dijon, St. Claude, and Grenoble.
The diocese of Lyons is also the birthplace of the Jesuit Père Coton (1564-1626), confessor of Henry IV and a native of Néronde, and Abbé Terray, controller general of finance under Louis XVI, a native of Boen (1715-1778).
The "Deacon of Vienne", martyred at Lyons during the persecution of 177, was probably a deacon installed at Vienne by the ecclesiastical authority of Lyons.
Gregory X was a former canon of Lyons, while Innocent V, as Peter of Tarantaise, was Archbishop of Lyons from 1272 to 1273.
It was at Lyons that Henry IV, the converted Calvinist king, married Marie de Medicis (9 December, 1600).