Area Code 864 is an area code in South Carolina that covers Greenville, Spartanburg, Anderson and the other parts of western South Carolina. Official language(s) English Capital Charleston(1670-1789) Columbia(1790-present) Largest city Columbia Largest metro area Greenville-Spartanburg Area Ranked 40th - Total 34,726 sq mi (82,965 km²) - Width 200 miles (320 km) - Length 260 miles (420 km) - % water 6 - Latitude 32°430N to 35°12... Greenvilles skyline from the south Greenville is the county seat of and largest city in Greenville CountyGR6 South Carolina, United States. ... Spartanburg is a city in Spartanburg County in South Carolina, a state of the United States of America, and 98 miles (158 km) northwest of Columbia. ... Anderson is a city located in Anderson County, South Carolina. ...