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Encyclopedia > Arginase 1
Arginase, drawn from PDB 1CEV.
Liver arginase
Identifiers
Symbol ARG1
HUGO 663
Entrez 383
OMIM 608313
RefSeq NM_000045
UniProt P05089
Other data
EC number 3.5.3.1
Locus Chr. 6 q23
Arginase, type II
Identifiers
Symbol ARG2
HUGO 664
Entrez 384
OMIM 107830
RefSeq NM_001172
UniProt P78540
Other data
EC number 3.5.3.1
Locus Chr. 14 q24.1

Arginase is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2Oornithine + urea. It is the final enzyme of the urea cycle. The Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. ... Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Short and long arms Chromosome. ... Chromosome 6 is one of the 23 pairs of chromosomes in humans. ... Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Short and long arms Chromosome. ... Chromosome 14 is one of the 23 pairs of chromosomes in humans. ... General Name, Symbol, Number manganese, Mn, 25 Chemical series transition metals Group, Period, Block 7, 4, d Appearance silvery metallic Atomic mass 54. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... Arginine (symbol Arg or R) is an α-amino acid. ... Impact of a drop of water. ... Ornithine is an amino acid, whose structure is: NH2-CH2-CH2-CH2-CHNH2-COOH Ornithine is one of the products of the action of the enzyme arginase on L-arginine, creating urea. ... Urea is an organic compound of carbon, nitrogen, oxygen and hydrogen, with the formula CON2H4 or (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Non-proprietary Names (rINN) in use in Europe. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... The reactions of the urea cycle. ...

Pathology

A lack of arginase can lead to a condition called "hyperargininemia" or arginemia. Arginemia (also called arginase deficiency) is a congenital disorder where arginase deficiency causes a high level of arginine in the blood. ...


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