Arginemia (also called arginase deficiency) is a congenital disorder where arginase deficiency causes a high level of arginine in the blood. Symptoms include hyperammonemia, metabolic alkalosis, convulsions, hepatomegaly, mental retardation and failure to grow. A congenital disorder is a medical condition that is present at birth. ... Arginase (EC 3. ... Arginine (Arg) is an α-amino acid. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... Hyperammonemia is a metabolic disturbance characterised by an excess of ammonia in the blood. ... Alkalosis refers to a condition reducing hydrogen ion concentration of arterial blood plasma. ... This article is about the medical condition. ... Hepatomegaly is an enlargement of the liver (swelling). ... Mental retardation (also called mental handicap and, as defined by the UK Mental Health Act 1983, mental impairment and severe mental impairment) is a term for a pattern of persistently slow learning of basic motor and language skills (milestones) during childhood, and a significantly below-normal global intellectual capacity as...