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Encyclopedia > Argininosuccinate
Argininosuccinic acid
Chemical structure of Argininosuccinate
Chemical formula  C10H18N4O6 
Molecular mass 290.273 g mol-1
Systematic name (2S)-2-[[N'-[(4S)-4-amino-4-
carboxy-butyl]carbamimidoyl]
amino]butanedioic acid
Complete data


Arginosuccinic acid is a chemical compound that belongs to the class of the amino acids. Some cells synthesize it from citrulline, aspartic acid and use it as a precursor for arginine in the urea cycle or Citrulline-NO cycle. The enzyme that catalyzes the reaction is ASS. A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless Atomic mass 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series Nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ... The molecular mass (abbreviated MM) of a substance, called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical compound is a chemical substance formed from two or more elements, with a fixed ratio determining the composition. ... An amino acid residue is what is left of an amino acid once a molecule of water has been lost (an H+ from the nitrogenous side and an OH- from the carboxylic side) in the formation of a peptide bond. ... The chemical compound citrulline is an α-amino acid (AA). ... Aspartic acid, also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins. ... Arginine (Arg) is an α-amino acid. ... The Urea Cycle is a cycle of biochemical reactions occurring in many animal organisms that produces urea from ammonia. ... Argininosuccinate synthetase is an enzyme that participates in the urea cycle, which is a sequence of chemical reactions that takes place in the cells of the liver. ...




See also


  Results from FactBites:
 
ASS - argininosuccinate synthetase (4070 words)
Argininosuccinate synthetase and argininosuccinate lyase, two cytoplasmic enzymes of the urea cycle, are released into the soluble phase in the absence of detergent when cells are disrupted.
Induction of astrocyte argininosuccinate synthetase and argininosuccinate lyase by dibutyryl cyclic AMP and dexamethasone.
Argininosuccinate synthetase and argininosuccinate lyase are soluble cytoplasmic enzymes of the urea cycle.
UCDC - Information for Physicians (1218 words)
Argininosuccinate Synthetase Deficiency (ASSD) (Citrullinemia I) Defects in argininosuccinate synthetase (ASS) affect the ability to incorporate ammonia into urea.
Argininosuccinate Lyase Deficiency affects the body’s ability to clear the nitrogen already incorporated into the urea cycle as argininosuccinate.
Diagnosis is based on the presence of large amounts of argininosuccinic acid in the bloodstream and direct enzymatic analysis of fibroblasts.
  More results at FactBites »


 
 

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