Arsphenamine is a drug that was used to treat syphilis and trypanosomiasis. It was the first modern chemotherapeutic agent. Sahachiro Hata found this compound in 1908 while studying in the laboratory of Paul Ehrlich, during a survey of thousands of compounds in search of anti-spirochete activity (the bacterium that causes syphilis is a spirochete). This compound was marketed under the trade name Salvarsan in 1910. After leaving Erlich's laboratory, Hata continued parallel investigation of the new medicine in Japan.^{[1] (http://en.wikipedia.org/wiki/Arsphenamine#fn_Hata)} Many drugs are provided in tablet form. ... Depression-era U.S. poster advocating early syphilis treatment Syphilis (historically called lues) is a sexually transmitted disease (STD) that is caused by a spirochaete bacterium, Treponema pallidum. ... Sleeping sickness or African trypanosomiasis is a parasitic disease in humans. ... Chemotherapy is the use of chemical substances to treat disease. ... For the American butterfly and overpopulation specialist, see Paul R. Ehrlich. ... Families Brachyspiraceae Leptospiraceae Spirochaetaceae The spirochaetes are a phylum of distinctive bacteria, which have long, helically coiled cells. ... This article is about brands in marketing. ... 1910 was a common year starting on Saturday (see link for calendar). ...

The structure has been believed to be:

structure of arsphenamine. ...

but in 2005, researchers determined Arsphenamine's structure to be a compound of a cyclic trimer and a pentamer[2] (http://www1.accsnet.ne.jp/~kentaro/yuuki/mow/0501/salvarsan.html). 2005 is a common year starting on Saturday of the Gregorian calendar. ...

It was the first important antisyphillitic, though was phased out in the 1930s by better arsenical compounds (neoarsphenamine), and eventually altogether by penicillin. Events and trends Technology Jet engine invented First atom was split with a particle accelerator Golden Age of radio begins in U.S. Science Nuclear fission discovered by Otto Hahn, Lise Meitner and Fritz Strassmann Pluto, the ninth planet from the Sun, is discovered by Clyde Tombaugh British biologist Arthur... General Name, Symbol, Number arsenic, As, 33 Series metalloids Group, Period, Block 15 (VA), 4, p Density, Hardness 5727 kg/m3, 3. ... Penicillin is a β-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. ...

References

1. ⇧ Izumi, Yoshio; and Isozumi, Kazuo. (2001). Modern Japanese medical history and the European influence. (http://www.kjm.keio.ac.jp/past/50/2/91.pdf) Keio Journal of Medicine 50 (2), 91-99. PMID 11450598.
2. Nicholas C. Lloyd, Hugh W. Morgan, Prof., Brian K. Nicholson, Prof. *, Ron S. Ronimus, Dr. (2005). The Composition of Ehrlich's Salvarsan: Resolution of a Century-Old Debate (http://www3.interscience.wiley.com/cgi-bin/abstract/109861322/ABSTRACT) Angewandte Chemie 117 (6), 963-966. PMID 15624113.