Mesalamine, also known as 5-aminosalicylic acid (5-ASA), is an anti-inflammatory drug used to treat inflammation of the rectum, mild to moderate ulcerative colitis and inflammation of the lower colon. Chemically, it is 5-amino-2-hydroxybenzoic acid. The empirical formula is C 7 H 7 NO 3 and its molecular weight is 153.14.
It is sold in the U.S. under the names:
CANASA: Rectal suppository with 500 mfg of mesalamine in a base of Hard Fat NF.
Approved by the FDA in 1997, Asacol (Aze-a-call) is a man-made compound that is taken by mouth to treat inflammatory disorders of the colon such as ulcerative colitis, Crohn's colitis, and other inflammatory conditions.
The active ingredient in Asacol, mesalamine (5-aminosalicylic acid, also referred to as 5-ASA), is the major active component of Azulfidine (sulfasalazine) which has been used for over 50 years in the treatment of inflammatory bowel disease.
One of the unique features of Asacol is the fact that the pill does not release its medication until it reaches the diseased area.
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