Ashikaga Yoshihide (Jp. 足利 義栄; 1538–1568) was the 14th shogun of the Ashikaga shogunate who reigned shortly from February to September of 1568 during the Japan. He was the grandson of the 11th shogun Ashikaga Yoshizumi.

Supported by Matsunaga Hisahide and retainers of Miyoshi Nagayoshi, Yoshihide became Seii Taishogun three years after the death of his cousin, the 13th shogun Ashikaga Yoshiteru. However, due to the political situation in Kyoto at the time, he was not able to enter the capital.

In September of 1568, Oda Nobunaga marched his armies into Kyoto, seized the capital, and installed Ashikaga Yoshiaki as the 15th shogun. Yoshihide, never once able to take his place in the capital, died soon afterwards from disease.