Atropa is a genus of plants in the nightshade family. Its best-known member is the deadly nightshade, Atropa belladonna. Its pharmacologically active ingredient is Atropine. The genus is named for one of the Three Fates, the one which cut the life thread.

In some older classifications, the Mandrake (Mandragora officinarum) is considered a species of the Atropa genus.