Co-amoxiclav is the British Approved Name, in the British Pharmacopoeia, for the combination antibiotic containing amoxicillin and clavulanic acid. This name, unlike co_trimoxazole, has not been widely adopted internationally and the combination product is usually referred to by various names such as amoxicillin with clavulanic acid or amoxicillin+clavulanate or simply by the trade name. Co_amoxiclav is currently marketed by GlaxoSmithKline under the trade name Augmentin®.
The combination of amoxicillin, a β-lactam antibiotic; with clavulanic acid, a β-lactamase inhibitor; results in an antibiotic with an increased spectrum of action and restored efficacy against β-lactamase producing amoxicillin-resistant bacteria.
Augmentin is used in the treatment of lower respiratory, middle ear, sinus, skin, and urinary tract infections that are caused by certain specific bacteria.
Augmentin ES-600, a stronger, oral-suspension form of the drug, is prescribed for certain stubborn ear infections that previous treatment has failed to clear up in children two and under, or those attending day care.
Augmentin XR is an extended-release form of the drug used to treat pneumonia and sinus infections.