Autoimmune hemolytic anemia (AIHA) is one type of hemolytic anemias caused by excessive hemolyisis and it is identified by auto-antibodies that react with RBCs. these antibodies are detected by the direct antiglobulin test also known as Coombs' test. Antiglobulin serum is added to washed RBCs from the patient; agglutination indicates the presence of immunoglobulin or compliment components bound to RBCs. Alternatively, mixing the patient's plasma with normal RBCs detect such antibodies in the plasma. [1] Hemolysis (alternative spelling haemolysis) is the excessive breakdown of red blood cells. ... RBC can mean: Real Business Cycle red blood cell Ripper-Burner-Converter Royal Bank of Canada RBC Center - indoor arena in Raleigh, North Carolina RBC Roosendaal,a Dutch football club This page concerning a three-letter acronym or abbreviation is a disambiguation page â a navigational aid which lists other pages... Wikipedia does not yet have an article with this exact name. ... Blood plasma is a component of blood. ... RBC can mean: Real Business Cycle red blood cell Ripper-Burner-Converter Royal Bank of Canada RBC Center - indoor arena in Raleigh, North Carolina RBC Roosendaal,a Dutch football club This page concerning a three-letter acronym or abbreviation is a disambiguation page â a navigational aid which lists other pages... In semantics, the patient is the passive part of a process. ... It has been suggested that this article or section be merged into agglutinative language. ... Schematic of antibody binding to an antigen An antibody is a protein complex used by the immune system to identify and neutralize foreign objects like bacteria and viruses. ... In semantics, the patient is the passive part of a process. ... The word plasma has a Greek root which means to be formed or molded (the word plastic shares this root). ... RBC can mean: Real Business Cycle red blood cell Ripper-Burner-Converter Royal Bank of Canada RBC Center - indoor arena in Raleigh, North Carolina RBC Roosendaal,a Dutch football club This page concerning a three-letter acronym or abbreviation is a disambiguation page â a navigational aid which lists other pages... The word plasma has a Greek root which means to be formed or molded (the word plastic shares this root). ...
Autoimmunehemolyticanemia is a group of disorders characterized by a malfunction of the immune system that produces autoantibodies, which attack red blood cells as if they were substances foreign to the body.
Autoimmunehemolyticanemia can also be caused by or occur with another disease, such as systemic lupus erythematosus, and it can follows the use of certain drugs, such as penicillin.
Autoimmunehemolyticanemia as the cause is confirmed when blood tests detect increased amounts of certain antibodies, either attached to red blood cells (direct antiglobulin or Coombs test) or in the liquid portion of the blood (indirect antiglobulin or Coombs test).
Idiopathic autoimmunehemolyticanemia is an acquired disease that occurs when antibodies form against a person's own red blood cells.
There are other types of immune hemolyticanemias where the cause may result from an underlying disease or medication.
Blood transfusions are given with caution, if indicated for severe anemia, because of the potential that blood may not be compatible and may bring on a reaction.