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BK virus in kidney transplantation: a case study Progress in Transplantation - Find Articles (850 words) |
 | BK virus creates an even greater challenge in posttransplant management and graft survival because of difficulty in diagnosing and treatment. |
| BK nephropathy develops in 1 % to 5% of transplant recipients, with loss of allograft function occurring in 50% of the cases. |
| An increased awareness of BK virus nephropathy is of great need in the transplant community as it is found in 1% to 5% of kidney transplant recipients. |
| CBER - Simian Virus 40 (SV40:) A Possible Human Polyomavirus Workshop (21092 words) |
| When we sequence the BK positive for the large T-antigen Rb pocket domains, it turns out in 12 different samples, ten from the tumor samples and two for normal tissue, that all the sequences were the same compared to the BK virus Dunlop strain. |
| Cells of the connective tissue are clearly associated with BK virus infection at epithelial cells as fibrocytes of the three organs, and specifically in the meningeal encephalitis we find epidermal cells associated with BK virus infection and interestingly, astrocytes. |
| And we assume that BK virus may be inducing a lot of undetectable chromosomal damage, even at lower multiplicities of infection that could potentially be occurring during a persistent infection. |
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