Basic Leucine zipper domain (bZIP domain)

CREB (top) is a transcription factor capable of binding DNAvia the bZIP domain (bottom) and regulating gene expression.

The bZIP domain is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates sequence specific DNA binding properties and the Leucine zipper that is required for the dimerization of two DNA binding regions. The DNA binding region comprises a number of basic aminoacids such as arginine and lysine Image File history File links Chains A and C of CREB-1 binding DNA. Drawn by User:Diberri based upon 1DH3. ... Image File history File links Chains A and C of CREB-1 binding DNA. Drawn by User:Diberri based upon 1DH3. ... In molecular biology, a transcription factor is a protein that binds DNA at a specific promoter or enhancer region or site, where it regulates transcription. ... Space-filling model of a section of DNA molecule Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions specifying the biological development of all cellular forms of life (and many viruses). ... Gene expression (also protein expression or often simply expression) is the process by which a genes information is converted into the structures and functions of a cell. ... Arginine is one of the 20 most common natural amino acids. ... Lysine is one of the 20 amino acids normally found in proteins. ...

bZIP domain containing proteins

• AP-1 fos/jun heterodimer that forms an transcription factor
• Jun-B transcription factor
• CREB cAMP response element transcription factor

June is the sixth month of the year in the Gregorian Calendar and one of four with the length of 30 days. ... In molecular biology, a transcription factor is a protein that binds DNA at a specific promoter or enhancer region or site, where it regulates transcription. ... CREB (top) is a transcription factor capable of binding DNA (bottom) and regulating gene expression. ...