Barbituric acid
Chemical name	2,4,6(1H,3H,5H)-Pyrimidinetrione
Chemical formula	C4H4N2O3
Molecular mass	128.09 g/mol
Melting point	245 °C
Boiling point	260 °C
Density	g/cm3
CAS number	67-52-7
SMILES	O=C1CC(=O)NC(=O)N1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Barbituric acid or malonylurea or 4-hydroxyuracyl is an organic compound based on a pyrimidine heterocyclic skeleton. It is an odorless powder soluble in hot water. Barbituric acid is the parent compound of a large class of barbiturates that have central nervous system depressant properties although barbituric acid itself is not pharmacologically active. The compound was discovered by the German chemist Adolf von Baeyer in 1864 by combining urea and malonic acid in a condensation reaction. Malonic acid has since been replaced by diethyl malonate. IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass (abbreviated MM) of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... The melting point of a solid is the temperature at which it changes state from solid to liquid. ... The boiling point of a substance is the temperature at which it can change its state from a liquid to a gas throughout the bulk of the liquid. ... Density (symbol: ρ - Greek: rho) is a measure of mass per unit of volume. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... Image File history File links Barbituric_acid. ... In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals) and 25 degrees Celsius (298. ... An organic compound is any member of a large class of chemical compounds whose molecules contain carbon, with the exception of carbides, carbonates, carbon oxides and gases containing carbon. ... Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. ... Heterocyclic compounds are substances which contain a ring structure as found in benzene and the aromatic compounds, or aromatic hydrocarbons, but in which other atoms than carbon, such as sulfur, oxygen or nitrogen are found as part of the ring. ... Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. ... Johann Friedrich Wilhelm Adolf von Baeyer (October 31, 1835 - August 20, 1917) was a German chemist who synthesized indigo, and was the 1905 recipient of the Nobel Prize in Chemistry. ... Urea is an organic compound of carbon, nitrogen, oxygen and hydrogen, with the formula CON2H4 or (NH2)2CO. Urea is also known as carbamide, especially in the recommended International Non-proprietary Names (rINN) in use in Europe. ... Malonic acid (from Latin malum = apple) (1,3-propanedioic acid) is a dicarboxylic acid with structure CH2(COOH)2. ... A condensation reaction (also known as a dehydration reaction or dehydration synthesis when water is lost) is a chemical reaction in which two molecules or moieties react and become covalently bonded to one another by the concurrent loss of a small molecule, often water or methanol. ... Diethyl malonate (DEM) has the structure (EtOOC)(CH2)(COOEt) Reactions Malonic ester synthesis DEM → monosubstituded acetic acid See also barbituric acid Categories: Malonates ...

Image File history File links Barbituric_acid_synthesis. ...

External links

• MSDS http://www.jtbaker.com [1]
• Barbituric acid strong formula.
• Barbituric acid J. B. Dickey and A. R. Gray Organic Syntheses, Coll. Vol. 2, p.60; Vol. 18, p.8 Online Article