The title of Baron Walpole was created in the Peerage of Great Britain in 1723 for Robert Walpole, eldest son of the prime minister Sir Robert Walpole, who was later created Earl of Orford and Viscount Walpole. In 1756 a cousin of the Walpole Earls of Orford was created Baron Walpole of Wolterton, also in the Peerage of Great Britain. With the extinction of the Earldom of Orford in 1797, the senior Barony of Walpole passed to Lord Walpole of Wolterton, who thus held both titles and was also created for Earl of Orford in 1806. The second Earldom of Orford became extinct in 1931, but the two baronies survive.

Barons Walpole (1723)

• Robert Walpole, 2nd Earl of Orford, 1st Baron Walpole (1701_1751)
• George Walpole, 3rd Earl of Orford, 2nd Baron Walpole (1730_1791)
• Horace Walpole, 4th Earl of Orford, 3rd Baron Walpole (1717-1797)
• Horatio Walpole, 1st Earl of Orford, 4th Baron Walpole (1723_1809)
• Horatio Walpole, 2nd Earl of Orford, 5th Baron Walpole (1752_1822)
• Horatio Walpole, 3rd Earl of Orford, 6th Baron Walpole (1783_1858)
• Horatio Walpole, 4th Earl of Orford, 7th Baron Walpole (1813-1894)
• Robert Horace Walpole, 5th Earl of Orford, 8th Baron Walpole (1854-1931)
• Robert Henry Montgomerie Walpole, 9th Baron Walpole (1913-1989)
• Robert Horatio Walpole, 10th Baron Walpole (b. 1938)

Barons Walpole of Wolterton (1756)

• Horatio Walpole, 1st Baron Walpole of Wolterton (1678-1757)
• Horatio Walpole, 2nd Baron Walpole of Wolterton (1723_1809) (became Baron Walpole in 1797 and Earl of Orford in 1806)
• See the earliest list for later holders of this title.