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Karl Adolph von Basedow was the first doctor to describe Basedow Syndrome, which is characterized by a triad of hyperthyroidism, goiter, and exophthalmos (bulging eyeballs).

Image File history File links Broom_icon. ... Hyperthyroidism (or overactive thyroid gland) is the clinical syndrome caused by an excess of circulating free thyroxine (T4) or free triiodothyronine (T3), or both. ... A goitre (or goiter) (Latin struma) is a swelling in the neck (just below adams apple or larynx) due to an enlarged thyroid gland. ... Exophthalmos (or proptosis) is a bulging of the eye anteriorly out of the orbit. ...

Symptoms

Symptoms include:

cardiac arrhythmias
increased pulse rate
weight loss in the presence of increased appetite
intolerance to heat
elevated basal metabolism rate
profuse sweating
weakness
elevated protein-bound iodine level
tremor
eyelid retraction and stare.

Cause

It is unknown, but it may be related to an autoimmune malfunction or disease. The ratio of onset is 4:1 in females. It is normally discovered in the third or fourth decade of life.

References

• Who named it? Basedow's syndrome or disease