Benzopyran is an polycyclicorganic compound that results from the fusion of a benzene ring to a heterocyclicpyran ring. Ketone derivatives of benzopyran (benzopyrones) include: Benzene An organic compound is any member of a large class of chemical compounds whose molecules contain carbon, with the exception of carbides, carbonates, carbon oxides and elementary carbon. ... Benzene, also known as benzol, is an organic chemical compound with the formula C6H6. ... Heterocyclic compounds are substances which contain a ring structure as found in benzene and the aromatic compounds, or aromatic hydrocarbons, but in which other atoms than carbon, such as sulfur, oxygen or nitrogen are found as part of the ring. ... In chemistry, a pyran is a six member aromatic heterocyclic ring with five carbons and one oxygen. ... Ketone group A ketone is either the functional group characterized by a carbonyl group linked to two other carbon atoms or a chemical compound that contains this functional group. ...
Chromone (1,4-benzopyrone); which constitutes the skeleton of many flavonoid compounds
Benzopyran derivatives of the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof possess the inhibitory activity on Maillard reaction and an antioxidizing effect, and therefore, are useful for the prevention and treatment of several diabetic complications, diseases induced by aging and several diseases caused by formation of peroxidized fat.
The benzopyran derivative (109.9 g) prepared in reference example 22 was dissolved in dimethylformamide (500 ml).
The compounds, of the present invention, shown in the following table 12 were obtained with using the benzopyran derivative prepared in reference example 18 by the same procedure as example 27 (with the proviso that the corresponding appropriate compounds were used instead of p-(2-hydroxyethyl)phenol and p-mercaptonitrophenol).
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