Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references
Betulin (lup-20(29)-ene-3β,28-diol)is an abundant naturally occuring triterpene. It is commonly isolated from the bark of birch trees and forms up to 30% of the dry weight of the extractive. It can be converted to Betulinic acid. Betulinic acid and its synthetic analouges exhibit anti malarial, anti inflamitory and anti HIV activity as well as showing cytotoxicity towards a number of tumour cell lines. IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The melting point of a solid is the temperature at which it changes state from solid to liquid. ... CLogP is shorthand for computed LogP, a measure of differential solubility or rather hydrophobicity as the octanol/water partition coefficient. ... In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals) and 25 degrees Celsius (298. ...
Betulin, a powdery substance in the outer bark of the birch tree, has been shown to help wounds heal faster and cut inflammation.
Betulin, its derivatives and other birch bark compounds also are being tested for effectiveness in treating HIV,the virus that causes AIDS, and respiratory syncytial virus (RSV), which can cause severe cold-like symptoms and pneumonia.
Examinations conducted, in Russian institute of pharmacology, showed that the complex of substances forming part of white part of birch bark possesses high antimutagenic activity, capable of lowering the number of mutations in the chromosomes and the genes, the frequency of the appearance of hereditary changes in the organism.
Betulin, a pentacyclic triterpenoid, was isolated from the bark of Betula papyrifera.
The antiviral efficacies of betulin on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) were evaluated using viral plaque reduction assays on Vero cells.
The cytotoxicity of betulin was examined on Vero cells using a neutral red uptake assay.
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