BioGlass® is a commercially available type of bioactive glass It is also known as 45S5 glass. It is composed of SiO2, Na2O, CaO and P2O5. Professor Larry Hench developed BioGlass® in the late 1960s. He was challenged by a MASH army officer to develop a material to help regenerate bone, as many Vietnam warveterans suffered badly from bone damage, such that most of them injured in this way lost their limbs. Bioactive glasses are a group of surface reactive glass-ceramics and include the original bioactive glass, Bioglass®. The biocompatibility of these glasses has led them to be investigated extensively for use as implant materials in the human body to repair and replace diseased or damaged bone. ... The 1960s decade refers to the years from 1960 to 1969, inclusive. ... The Mobile Army Surgical hospital (MASH) refers to a United States Army medical unit serving as a fully functional hospital in a combat area of operations. ... This article is about the skeletal organs. ... Combatants Republic of Vietnam United States Republic of Korea Thailand Australia New Zealand The Philippines National Front for the Liberation of South Vietnam Democratic Republic of Vietnam People’s Republic of China Democratic Peoples Republic of Korea Strength US 1,000,000 South Korea 300,000 Australia 48,000... Former crewmembers of the battleship Missouri pose for photos shortly after the Anniversary of the End of World War II ceremony, held aboard the famous ship. ...
The key composition features of BioGlass® is that it contains less than 60mol% SiO2, high Na2O and CaO contents, high CaO/P2O5 ratio, which makes BioGlass® highly reactive to aqueous medium and bioactive.
High boiactivity is the main advantage of BioGlass®, while its disadvantage includes mechanical weakness, low fracture toughness due to amorphous 2-dimensional glass network. The bending strength of most BioGlass® is in the range of 40-60MPa, which is not enough for load-bearing application. While its Young's modulus is 30-35GPa, very close to that of cortical bone.
A major object of the invention therefore is to remove the disadvantages inherent to bioglass materials up till now and to provide a bioglass material that may be used for implants without any need to be coated on dense alumina or metal.
Any suitable bioglass or biologically active glass that is capable of bonding to bone or other living tissue may be employed in the present invention.
It may be concluded from table 1 that the mechanical properties of the bioglass (in terms of strength and ductility) have been considerably improved by the incorporation of ductile metal fibers therein.
BioGlass® is a commercially available type of bioactive glass.
Professor Larry Hench developed BioGlass® in the late 1960s.
He was challenged by a MASH army officer to develop a material to help regenerate bone, as many Vietnam war veterans suffered badly from bone damage, such that most of them injured in this way lost their limbs.
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