This article is about the location in Scotland. See also Blantyre, Malawi.

Blantyre is a burgh in South Lanarkshire, Scotland. Essentially a large suburb of Hamilton (Blantyre's pop. c17 000), it is best-known as the birthplace of David Livingstone. His former house is now a museum. Also nearby is Bothwell Castle, dating from the thirteenth century.

Blantyre is the site for the famous Blantyre Mining Disaster, where 207 miners were killed when a coal mine exploded due to methane gas. There is little doubt that safety regulations were not adhered to. Christy Moore wrote a song about this disaster.