The blastocyst is an early stage of the human (or any other mammal) development early in pregnancy. It is the structure formed in early human embryogenesis, after the formation of the blastocele, but before implantation. It possesses an inner cell mass, or embryoblast, and an outer cell mass, or trophoblast. The human blastocyst comprises 70-100 cells. It is preceded by a zygote, the fertilized egg cell, and succeeded by an embryo. Image File history File links Blastocyst. ... This article does not cite any references or sources. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Elseviers logo. ... Human embryogenesis is the process of cell division and cellular differentiation of the human embryo during early prenatal development. ... A blastocoel(e) or blastocele or cleavage cavity or segmentation cavity is the central region of a blastula (or blastosphere). ... Implantation is a phenomenon in prenatal development, i. ... The inner cell mass is surrounded by the single cell layer of cells called trophoblast. ... The trophoblast (from Greek threphein: to feed) is considered to be the first of all embryonic annexes. ... Drawing of the structure of cork as it appeared under the microscope to Robert Hooke from Micrographia which is the origin of the word cell being used to describe the smallest unit of a living organism Cells in culture, stained for keratin (red) and DNA (green) The cell is the... It has been suggested that Biparental zygote be merged into this article or section. ... For other uses, see Embryo (disambiguation). ...
Recently the inner cell mass has become a source for embryonic stem cells. Mouse embryonic stem cells. ...
This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant. The public domain comprises the body of all creative works and other knowledge—writing, artwork, music, science, inventions, and others—in which no person or organization has any proprietary interest. ... An illustration from the 1918 edition Henry Grays Anatomy of the Human Body (or Grays Anatomy as it has more commonly become known) is an anatomy textbook widely regarded as a classic work on human anatomy. ...
Germ layer: Ectoderm (Neuroectoderm) - Endoderm - Mesoderm (Chorda-, Paraxial, Intermediate, Lateral plate) - Splanchnopleure/Somatopleure Human embryogenesis is the process of cell division and cellular differentiation of the human embryo during early prenatal development. ... This article or section is in need of attention from an expert on the subject. ... For other uses, see Embryo (disambiguation). ... This article is about prenatal development in humans. ... âUnborn childâ redirects here. ... This article does not cite any references or sources. ... The following list describes a timeline of specific changes in human prenatal development by week of gestational age. ... It has been suggested that Biparental zygote be merged into this article or section. ... Morula is a stage of embryonic development in animals, including the 16-cell phase, the 32-cell phase, and the 64-cell phase. ... A blastomere is the structure which results from the divisions of a fertilised egg during embryonic development . ... Blastulation. ... Blastulation. ... A blastocoel(e) or blastocele or cleavage cavity or segmentation cavity is the central region of a blastocyst. ... The inner cell mass is surrounded by the single cell layer of cells called trophoblast. ... This article, image, template or category should belong in one or more categories. ... The hypoblast is a tissue type from the inner cell mass. ... In embryology, the epiblast is a feature present during gastrulation. ... The archenteron is an indentation that forms early on in a developing blastula. ... The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development. ... It has been suggested that this article or section be merged with Embryogenesis. ... The primitive knot (or Primitive node) is the organizer for gastrulation in vertebrates. ... A blastopore is an opening into the archenteron during the embryonic stages of an organism. ... A shallow groove, the primitive groove, appears on the surface of the primitive streak, and the anterior end of this groove communicates by means of an aperture, the blastophore, with the yolk-sac. ... 1 - blastula, 2 - gastrula; orange - ectoderm, red - endoderm. ... It has been suggested that epiboly be merged into this article or section. ... Organs derived from each germ layer. ... The ectoderm is outermost of the three germ layers of the developing embryo, the other two being the mesoderm and the endoderm. ... Neuroectoderm is the term for ectoderm which receives inhibitory signals from proteins such as noggin, which leads to the development of the nervous system from this tissue. ... The endoderm, sometimes refered to as entoderm, is one of the three germ layers of the developing embryo, the other two being the ectoderm and the mesoderm. ... The mesoderm is one of the three germ layers in the early developing embryo, the other two layers being the ectoderm and the endoderm. ... Chordamesoderm is a type of mesoderm that lies along the central axis, under the neural tube. ... Paraxial mesoderm is the area of mesoderm that forms just lateral to the neural tube on both sides. ... Intermediate mesoderm is a type of mesoderm that is located between the paraxial mesoderm and the lateral plate. ... Lateral plate mesoderm (or hypomere) is a type of mesoderm that is found at the periphery of the embryo. ... In the anatomy of an embryo, the splanchnopleure is a structure created during embryogenesis when the lateral mesoderm splits into two layers. ... When the lateral mesoderm splits into two layers, the outer (or somatic) one becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure. ...
Candidates for blastocyst transfer are patients with at least six embryos and under the age of 40.
The possible disadvantages of blastocyst transfer include a longer time interval between retrieval and transfer, fewer embryos that can be frozen, and the potential for lack of transfer due to degeneration and arrest of the embryos prior to the blastocyst stage.
The decision to perform blastocyst culture and transfer is based on several factors including patient age, egg age in cases of donor egg, the number of eggs retrieved, previous IVF success, and perhaps most importantly, the embryo grade and cell count on day three of culture.
Until recently, culture of embryos, in the laboratory, to the blastocyst stage was very difficult because the several culture media that were used to supply nutrients to the embryos were inadequate for extended embryo growth in the laboratory.
Blastocyst transfer may become the routine method of embryo transfer or it may be limited to selected subgroups of patients.
The preparations for blastocyst culture are somewhat different for the laboratory and the transfer usually takes place on day 5 rather than day 3, so it is recommended that a discussion take place with your physician prior to your retrieval in order to decide if blastocyst transfer is right for you.