"Blue 1" redirects here. For the airline, see Blue1. Blue1 is an airline based in Helsinki, Finland. ...

Brilliant Blue FCF

Brilliant Blue FCF (also known as FD&C Blue No.1, Food Blue 2, Acid Blue 9, D&C Blue No. 4, Alzen Food Blue No. 1, Alphazurine, Atracid Blue FG, Erioglaucine, Eriosky blue, Patent Blue AR, Xylene Blue VSG, and C.I. 42090) is a colorant that may be added to foods to induce a color change. It is denoted by E Number E133. It has the appearance of a reddish-blue powder. It is soluble in water; solution has maximum absorption at about 630 nm. Image File history File links No higher resolution available. ... Image File history File links No higher resolution available. ... The United States Federal Food, Drug, and Cosmetic Act (FD&C) is a set of laws passed by Congress in 1938 giving authority to the Food and Drug Administration to oversee the safety of food, drugs, and cosmetics. ... A colourant is something added to something else to induce a change in colour. ... For the mathematical constant see: E (mathematical constant). ... A nanometre (American spelling: nanometer) is 1. ...

It is a synthetic dye derived from coal tar. It can be combined with tartrazine (E102) to produce various shades of green. It is often found in ice cream, tinned processed peas, dairy products, sweets, and drinks. It is also used in soaps, shampoos, and other hygiene and cosmetics applications. In chemistry, chemical synthesis is purposeful execution of chemical reactions in order to get a product, or several products. ... Coal tar is the liquid by-product of the distillation of coal to make coke. ... “Yellow 5” redirects here. ... Missing image Ice cream is often served on a stick Boxes of ice cream are often found in stores in a display freezer. ... For the American naval slang term, see destroyer. ... Binomial name L. Percentages are relative to US recommendations for adults. ... A dairy farm near Oxford, New York in the United States. ... This article is about the computer protocol. ... Shampoo is a common hair care product used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant particles that gradually build up in hair. ...

It has previously been banned in Austria, Belgium, Denmark, France, Germany, Greece, Italy, Norway, Spain, Sweden, and Switzerland among others but has been certified as a safe food additive in the EU and is today unbanned in most of the countries. In the United States production exceeds 1 million pounds annually, and daily consumption is around 16 mg per person. The pound or pound-mass (abbreviations: lb, lbm, or sometimes in the United States, #) is a unit of mass (sometimes called weight in everyday parlance) in a number of different systems, including English units, Imperial units, and United States customary units. ...

It has the capacity for inducing an allergic reaction^{[citation needed]}. An allergy is an abnormal, acquired sensitivity to a given substance, including pollen, drugs, or numerous environmental triggers. ...

It is one of the colorants that the Hyperactive Children's Support Group and the Feingold Association recommends to be eliminated from the diet of children. The National Institutes of Health concluded that color additives do not cause hyperactivity.^[1]

Its CAS number is [3844-45-9] and its SMILES structure is CC[N+](CC4=CC (S(=O)([O-])=O) =CC=C4)=C(C=C3) /C=CC3=C(C2=C (S(=O)([O-])=O) C=CC=C2)/C1=C C=C(N(CC)CC5=C C=CC(S(=O)([O-]) =O)=C5)C=C1. It is usually a disodium salt. The diammonium salt has CAS number [2650-18-2]. Calcium and potassium salts are also permitted. It can also appear as an aluminium lake. CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... Lake pigments are pigments made by precipitating a dye on an inert substance, such as calcium sulphate. ...

The chemical formation is C₃₇H₃₄N₂Na₂O₉S₃. The dye is poorly absorbed from the gastro-intestinal tract and 95% of the absorbed dye can be found in the feces.

References

1. ^ NIH concludes color additives do not cause hyperactivity, http://www.cfsan.fda.gov/~dms/qa-adf20.html

• W. H. Hansen, O. G. Fitzhugh, A. A. Nelson, K. J. Davis, (1966). "Chronic toxicity of two food colors, Brilliant Blue FCF and Indigotine". Toxicology and Applied Pharmacology 8 (1): 29-36. DOI:10.1016/0041-008X(66)90097-4. 
• J. F. Borzelleca, K. Depukat, J. B. Hallagan (1990). "Lifetime toxicity/carcinogenicity studies of FD & C blue No. 1 (Brilliant blue FCF) in rats and mice". Food and Chemical Toxicology 28 (4): 221-235. DOI:10.1016/0278-6915(90)90034-K. 
• J. P. Brown, A. Dorsky, F. E. Enderlin, R. L. Hale, V. A. Wright, T. M. Parkinson (1980). "Synthesis of ¹⁴C-labelled FD & C blue no. 1 (brilliant blue FCF) and its intestinal absorption and metabolic fate in rats". Food and Cosmetics Toxicology 18 (1): 1-5. DOI:10.1016/0015-6264(80)90002-4. 

A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ... A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ... A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ...

External links

• The Chemistry of Colors
• FDA Public Health Advisory on use in enteral feeding
• The Hyperactive Children's Support Group
• The Feingold Association
• The Feingold Diet; Dubious Benefits, Subtle Risks
• Some more details, other common names