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Encyclopedia > Bronchospasm

Bronchospasm is a difficulty in breathing caused by a sudden constriction of the muscles in the walls of the bronchioles. It is caused by the release (degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins. A mast cell (or mastocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. ... Categories: Wikipedia cleanup | Biology stubs | Blood and immune system cells ... Anaphylatoxin, or anaphylotoxin, is a fragment (C3a, C4a or C5a) of the complement system that triggers degranulation of (release of substances from) mast cells or basophils, which is an important part of the immune system in all kinds of inflammation and especially as part of defense against parasites. ...


Bronchospasm appears as the feature of asthma, chronic bronchitis, anaphylaxis, and as a possible side-effect of the drug Pilocarpine (which is used to treat illness resulted in the ingestion of deadly nightshade as well as other things). The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in mucous production; this reduces the amount of oxygen that is available to the individual causing breathlessness, coughing and hypoxia (that can cause cyanosis). Sebastian Telfair of the Boston Celtics, suffered from this on November 10, 2006 clinically as a persistent cough that produces sputummatter that is coughed up from the respiratory tract, for at least three months in two consecutive years. ... In medicine, anaphylaxis is a severe and rapid systemic allergic reaction. ... Hypoxia is a pathological condition in which the body as a whole (generalised hypoxia) or region of the body (tissue hypoxia) is deprived of adequate oxygen supply. ... Cyanosis refers to the bluish coloration of the skin due to the presence of deoxygenated hemoglobin in blood vessels near the skin surface. ...


  Results from FactBites:
 
Bronchospasm- Health Encyclopedia and Reference (838 words)
Bronchospasm is an abnormal contraction of the smooth muscle of the bronchi, resulting in an acute narrowing and obstruction of the respiratory airway.
Bronchospasm is a chief characteristic of asthma and bronchitis.
Bronchospasm is a temporary narrowing of the bronchi (airways into the lungs) caused by contraction of the muscles in the lung walls, by inflammation of the lung lining, or by a combination of both.
Bronchospasm - Wikipedia, the free encyclopedia (183 words)
Bronchospasm is a difficulty in breathing caused by a sudden constriction of the muscles in the walls of the bronchioles.
It is caused by the release (degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins.
Bronchospasm appears as the feature of asthma, chronic bronchitis, anaphylaxis, and as a possible side-effect of the drug Pilocarpine (which is used to treat illness resulted in the ingestion of deadly nightshade as well as other things).
  More results at FactBites »


 

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