Buckhorn, Missouri is a former community on Missouri State Highway 17 at its junction with Interstate 44 in Pulaski County. It is also on historic U.S. Highway 66. In 2003, it was annexed by nearby Waynesville. Numerous businesses line the highway at this location. Missouri State Highway 17 is a highway in central and southern Missouri. ... MAJOR JUNCTIONS JUNCTION MILEPOST I-40 Oklahoma 120 I-35 Oklahoma 130-135 I-55 Missouri 290 Legend BROWSE STATE HWYS Interstate 44 is an interstate highway in the central United States. ... Pulaski County is a county located in the state of Missouri. ... U.S. Highway 66 or Route 66 was a highway in the U.S. Highway system. ... 2003 (MMIII) was a common year starting on Wednesday of the Gregorian calendar. ... Waynesville is a city located in Pulaski County, Missouri. ...