Butalbital
Systematic (IUPAC) name
5-(2-methylpropyl)-5-(2-propenyl)- 2,4,6(1H,3H,5H)-pyrimidinetrione
Identifiers
CAS number	77-26-9
ATC code	?
PubChem	2481
DrugBank	APRD00266
Chemical data
Formula	C11H16N2O3
Mol. mass	224.256
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	about 35 hours[1]
Excretion	?
Therapeutic considerations
Pregnancy cat.	? Image File history File links Butalbital. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... The DrugBank database available at the University of Alberta is a unique bioinformatics and cheminformatics resource that combines detailed drug (i. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
Legal status	Schedule III(US) The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... The Controlled Substances Act (CSA) was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970. ... Motto: (Out Of Many, One) (traditional) In God We Trust (1956 to date) Anthem: The Star-Spangled Banner Capital Washington D.C. Largest city New York City None at federal level (English de facto) Government Federal constitutional republic  - President George Walker Bush (R)  - Vice President Dick Cheney (R) Independence from...
Routes	?

Butalbital, 5-allyl-5-isobutylbarbituric acid, is a barbiturate with an intermediate duration of action. It has the same chemical formula as talbutal but a different structure. Butalbital is often combined with other medications, such as acetaminophen or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA approved for the treatment of tension headaches. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. ... Talbutal (Lotusate®), also called 5-allyl-5-isobutylbarbituric acid, is a barbiturate with a short to intermediate duration of action. ... Hurting redirects here. ... A headache is a condition of pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ... The Food and Drug Administration (FDA) is an agency of the United States Department of Health and Human Services and is responsible for regulating food (humans and animal), dietary supplements, drugs (human and animal), cosmetics, medical devices (human and animal) and radiation emitting devices (including non-medical devices), biologics, and... Tension headaches, which were recently renamed tension-type headaches by the International Headache Society, are the most common type of headaches. ...

Combinations include:

• butalbital and acetaminophen (Axocet®, Bucet®, Bupap®, Cephadyn®, Dolgic®, Phrenilin®, Phrenilin Forte®, Sedapap®)
• butalbital, acetaminophen, and caffeine (Fioricet®, Esgic®, Esgic-Plus®)
• butalbital and aspirin (Axotal®)
• butalbital, aspirin, and caffeine (Fiorinal®, Fiormor®, Fiortal®, Fortabs®, Laniroif®)
• butalbital, acetaminophen, caffeine, and codeine phosphate (Fioricet #3 with Codeine®)
• butalbital, aspirin, caffeine, and codeine phosphate (Fiorinal #3 with Codeine®)

Fioricet (50/40/325)

Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. ... Generic Fioricet (50/40/325) Fioricet and Esgic are brand name drugs made from a combination of acetaminophen (325 mg), butalbital (a barbiturate, 50 mg), and caffeine (40 mg). ... Aspirin or acetylsalicylic acid (acetosal) is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. ... Fiorinal is a combination analgesic medication that consists of acetylsalicylic acid, the barbiturate butalbital and caffeine. ... Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ... Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. ... Codeine (INN) or methylmorphine is an opioid used for its analgesic, antitussive and antidiarrheal properties. ... Generic Fioricet (50/40/325) Fioricet and Esgic are brand name drugs made from a combination of acetaminophen (325 mg), butalbital (a barbiturate, 50 mg), and caffeine (40 mg). ... Aspirin or acetylsalicylic acid (acetosal) is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ... Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. ... Codeine (INN) or methylmorphine is an opioid used for its analgesic, antitussive and antidiarrheal properties. ... Fiorinal is a combination analgesic medication that consists of acetylsalicylic acid, the barbiturate butalbital and caffeine. ... Image File history File linksMetadata Fioricet. ... Image File history File linksMetadata Fioricet. ...

Side effects

Side effects for any drug are difficult to predict, but commonly reported side effects for Butalbital include:

• Dizziness
• Drowsiness
• Intoxicated feeling
• Light-headedness
• Nausea
• Sedation
• Addiction
• Severe impairment of judgement

There are other potential side effects, this list should not be considered all-inclusive. // Pre-syncope is a sensation of feeling faint. ... Somnolence (or drowsiness, or hypersomnia) is a state of near-sleep, a strong desire for sleep, or sleeping unusually long periods. ... ... For the Beck song, see Nausea (song). ... Sedation is a medical procedure involving administration of sedative drugs, generally to facilitate a medical procedure, such as endoscopy, vasectomy, or minor surgery with local anaesthesia. ... Addiction is a chronic or recurrent condition proposed to be precipitated by one or more of the following: genetic, biological/pharmacological and social factors. ... Judgment or judgement implies a balanced weighing up of evidence preparatory to making a decision. ...

Dangers and Risks

Butalbital is a physically and psychologically addictive barbiturate. Butalbital should not be mixed with alcohol due to increased risk of intoxication. Physical dependence describes increased tolerance of a drug combined with a physical need of the drug to function. ... Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. ... Functional group of an alcohol molecule. ...

There are other potential risks; this list should not be considered all-inclusive.

External links

Butalbital. On-line Medical Dictionary. Retrieved on 2005 June 26. 2005 (MMV) was a common year starting on Saturday of the Gregorian calendar. ... June 26 is the 177th day of the year (178th in leap years) in the Gregorian calendar, with 188 days remaining. ...

Butalbital and Acetaminophen (Systemic). MedicinePlus Drug Information. Retrieved on 2006 December 31. For the Manfred Mann album, see 2006 (album). ... December 31 is the 365th day of the year (366th in leap years) in the Gregorian Calendar. ...

Controlled Substances in Schedule III. Drug Enforcement Administration (2007). Retrieved on 2007 January 13. 2007 (MMVII) is the current year, a common year starting on Monday of the Gregorian calendar and the Anno Domini (common) era. ... January 13 is the 13th day of the year in the Gregorian calendar. ...