FACTOID # 98: Members of the armed forces and the police cannot vote in the Dominican Republic.
 
 Home   Encyclopedia   Statistics   Countries A-Z   Flags   Maps   Education   Forum   FAQ   About 
 
WHAT'S NEW
RECENT ARTICLES
More Recent Articles »
 

FACTS & STATISTICS    Simple view

  1. Select countries to view: (hold down Control key and click to select several)

     

     

    Compare:

     

     

  1. Select fact or statistic: (* = graphable)

     

     

     

  2. (OPTIONAL) Compare to statistic: (both need to be graphable)

     

     

     

  3. View result as:

     

       
(OR) SEARCH ALL encyclopedia, stats & forums:   

Encyclopedia > CD117
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Identifiers
Symbol(s) KIT
Entrez 3815
OMIM 164920
RefSeq NM_000222
UniProt P10721
Other data
Locus Chr. 4 q11-q12

This CD molecule is the membrane receptor for stem cell factor (SCF), also known as "steel factor" or "c-kit ligand". Steel factor is a polypeptide that activates bone marrow precursors of a number of blood cells, but its receptor is also present on other cells. C-kit mutations in the interstitial cells of Cajal in the digestive tract are probably the key to gastrointestinal stromal tumors (GISTs), and explain the efficacy of imatinib in the management of these rare malignancies. Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... Short and long arms Chromosome. ... Chromosome 4 is one of the 23 pairs of chromosomes in humans. ... The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ... In biochemistry, a receptor is a protein on the cell membrane or within the cytoplasm that binds to a specific factor (a ligand), such as a neurotransmitter, hormone, or other substance, and initiates the cellular response to the ligand. ... Peptides are the family of molecules formed from the linking, in a defined order, of various amino acids. ... Grays Anatomy illustration of cells in bone marrow. ... A blood cell is any cell of any type normally found in blood. ... Interstitial cells of Cajal are found in the Gastrointestinal tract ICC:s have an unstable membrane potential (between -65 and -45mV), forming a sort of pacemaker. ... For the Physics term GUT, please refer to Grand unification theory The gastrointestinal or digestive tract, also referred to as the GI tract or the alimentary canal or the gut, is the system of organs within multicellular animals which takes in food, digests it to extract energy and nutrients, and... Endoscopic image of GIST in fundus of stomach, seen on retroflexion. ... Imatinib is a drug used to treat certain types of cancer. ... A rare disease (sometimes known as an orphan disease) has such a low prevalence in a population that a doctor in a busy general practice would not expect to see more than one case a year. ...


Cluster of differentiation (CD) molecules are markers on the cell surface, as recognized by specific sets of antibodies, used to identify the cell type, stage of differentiation and activity of a cell. The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ...


See also

Tyrosine kinases are a subclass of protein kinase, see there for the principles of protein phosphorylation A tyrosine kinase (EC 2. ...

External links

  • MeSH Proto-Oncogene+Proteins+c-kit


 

COMMENTARY     


Share your thoughts, questions and commentary here
Your name
Your comments
Please enter the 5-letter protection code

Want to know more?
Search encyclopedia, statistics and forums:

 


Lesson Plans | Student Area | Student FAQ | Reviews | Press Releases |  Feeds | Contact
The Wikipedia article included on this page is licensed under the GFDL.
Images may be subject to relevant owners' copyright.
All other elements are (c) copyright NationMaster.com 2003-5. All Rights Reserved.
Usage implies agreement with terms.