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Encyclopedia > CD11c
integrin, alpha X (complement component 3 receptor 4 subunit)
Identifiers
Symbol(s) ITGAX CD11C
Entrez 3687
OMIM 151510
RefSeq NM_000887
UniProt P20702
Other data
Locus Chr. 16 p11.2

CDC11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... In biology and evolutionary computation, a locus is the position of a gene (or other significant sequence) on a chromosome. ... Chromosome 16 is one of the 23 pairs of chromosomes in humans. ... NIGGGGGGGGAAAAAAAAAAAAAAAA PLEASE A transmembrane protein is an integral membrane protein that spans from the internal to the external surface of the biological membrane or lipid bilayer in which it is embedded. ... Trinomial name Homo sapiens sapiens Linnaeus, 1758 Humans, or human beings, are bipedal primates belonging to the mammalian species Homo sapiens (Latin for wise man or knowing man) under the family Hominidae (known as the great apes). ... Dendritic cells (DC) are immune cells and form part of the mammal immune system. ... MONOCYTES: Plural of monocyte. ... Macrophages (Greek: big eaters) are cells found in tissues that are responsible for phagocytosis of pathogens, dead cells and cellular debris. ... Neutrophil granulocytes (commonly referred to as neutrophils) are a class of white blood cells and are part of the immune system. ... B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ... Respiratory burst is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells. ... Hairy cell leukemia is a type of chronic lymphoid leukemia. ...


See also

An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. ...

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